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一氧化碳中毒:超越生存——土耳其样本的死亡率、发病率和危险因素。

Carbon monoxide poisoning: beyond survival - mortality, morbidities, and risk factors, a Turkey sample.

机构信息

Family Medicine, Adiyaman Provincial Health Directorate, Adıyaman, Turkey.

Public Health, Adiyaman Provincial Health Directorate, Adıyaman, Turkey.

出版信息

PeerJ. 2023 Sep 28;11:e16093. doi: 10.7717/peerj.16093. eCollection 2023.

Abstract

BACKGROUND

We aimed to investigate the effect of poisoning on mortality leading to new morbidities in people who survived the poisoning.

METHODS

The descriptive-retrospective study evaluated all carbon monoxide poisoning cases between 2012 and 2022 in the Adiyaman. For the fatality, all cases were followed up through Turkey's death notification system until the end of 2022. One-year health records of cases treated as inpatients in Adiyaman hospitals were analyzed for nine diagnoses. A total of 4,395 carbon monoxide cases, recorded over 11 years, were all noted to be accidental cases.

RESULTS

The rate of carbon monoxide poisoning in Adıyaman was calculated as 63.2 per hundred thousand. A total of 87 (2%) of the cases died. The population's hospitalization rate was 1.71, while the mortality rate was 1.25 in a hundred thousand. Among the cases, the hospitalization rate was 2.7, and the admission to intensive care rate was 1.7. The fatality rate was 6.5% for those hospitalized and 12.2% for those admitted to the intensive care unit. The highest fatality rate was 65.5% in patients aged 65 and above. One out of five morbidities was developed in 8.4% of cases within one year. The fatality rate of those who developed morbidities (40%) was higher than those who did not (5.5%). Being male posed a 1,886-fold risk for mortality, and each increase in age posed a 1,086-fold risk for mortality.

CONCLUSION

Individuals who had carbon monoxide poisoning should be followed up closely for one year after poisoning due to the possibility of the emergence of new morbidities that increase the risk of mortality.

摘要

背景

本研究旨在探讨中毒对幸存者新发病和死亡的影响。

方法

描述性回顾性研究评估了 2012 年至 2022 年期间在阿达纳发生的所有一氧化碳中毒病例。对于死亡病例,通过土耳其死亡通知系统对所有病例进行了随访,直至 2022 年底。分析了在阿达纳医院住院治疗的病例的 9 种诊断的 1 年健康记录。在 11 年期间共记录了 4395 例一氧化碳中毒病例,均为意外中毒。

结果

阿达纳的一氧化碳中毒发生率为每 10 万人 63.2 例。共有 87 例(2%)死亡。该人群的住院率为 1.71%,每 10 万人的死亡率为 1.25%。在病例中,住院率为 2.7%,进入重症监护病房的比例为 1.7%。住院患者的死亡率为 6.5%,重症监护病房患者的死亡率为 12.2%。年龄在 65 岁及以上的患者死亡率最高,为 65.5%。在一年内,有 8.4%的患者发生了 1 种以上的并发症。发生并发症的患者(40%)的死亡率高于未发生并发症的患者(5.5%)。男性的死亡率是女性的 1886 倍,年龄每增加 1 岁,死亡率增加 1086 倍。

结论

由于可能出现新的增加死亡率的并发症,一氧化碳中毒患者在中毒后应密切随访 1 年。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/952c/10542819/a0062dff8373/peerj-11-16093-g001.jpg

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