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非裔美国人和西班牙裔多发性硬化症患者神经眼科疾病的叙述性综述。

A narrative review of neuro-ophthalmologic disease in African Americans and Hispanics with multiple sclerosis.

作者信息

Tardo Lauren, Salter Amber, Truong-Le Melanie, Horton Lindsay, Blackburn Kyle M, Sguigna Peter V

机构信息

Department of Neurology, The University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd, Dallas, TX 75390-8806, USA.

Department of Neurology, The University of Texas Southwestern Medical Center, Dallas, TX, USA.

出版信息

Ther Adv Chronic Dis. 2023 Sep 30;14:20406223231202645. doi: 10.1177/20406223231202645. eCollection 2023.

DOI:10.1177/20406223231202645
PMID:37790945
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10542320/
Abstract

Multiple sclerosis (MS) is the most common non-traumatic cause of disability in young people, with vision loss in the disease representing the second largest contributor to disability. In particular, African-American patients with MS are noted to have lower vision than their Caucasian counterparts. In this review, we examine the disparities in eye diseases in the MS population with our gaps in knowledge and discuss the underlying nature of pathological disparities.

摘要

多发性硬化症(MS)是年轻人非创伤性致残的最常见原因,该疾病导致的视力丧失是致残的第二大因素。特别是,患有MS的非裔美国患者的视力低于白人患者。在本综述中,我们研究了MS人群眼部疾病的差异以及我们在知识方面的差距,并讨论了病理差异的潜在本质。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2461/10542320/48304a9e1148/10.1177_20406223231202645-fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2461/10542320/d11c475af0b5/10.1177_20406223231202645-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2461/10542320/8ac745e7baa2/10.1177_20406223231202645-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2461/10542320/48304a9e1148/10.1177_20406223231202645-fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2461/10542320/d11c475af0b5/10.1177_20406223231202645-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2461/10542320/8ac745e7baa2/10.1177_20406223231202645-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2461/10542320/48304a9e1148/10.1177_20406223231202645-fig3.jpg

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J Neurol Sci. 2023 Jun 15;449:120669. doi: 10.1016/j.jns.2023.120669. Epub 2023 May 3.
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Selective vulnerability of brainstem and cervical spinal cord regions in people with non-progressive multiple sclerosis of Black or African American and European ancestry.黑人或非裔美国人以及欧洲血统的非进行性多发性硬化症患者脑干和颈脊髓区域的选择性易损性。
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Multiple sclerosis progression: time for a new mechanism-driven framework.
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Lancet Neurol. 2023 Jan;22(1):78-88. doi: 10.1016/S1474-4422(22)00289-7. Epub 2022 Nov 18.
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Trans-Synaptic Degeneration Following Acute Optic Neuritis in Multiple Sclerosis.多发性硬化症急性视神经炎后的跨突触变性。
Ann Neurol. 2023 Jan;93(1):76-87. doi: 10.1002/ana.26529. Epub 2022 Oct 22.
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