Harrison Jessie C, Figh Matthew, Shah Heather
Research, Alabama College of Osteopathic Medicine, Dothan, USA.
General Surgery, Decatur Morgan Hospital, Decatur, USA.
Cureus. 2023 Aug 31;15(8):e44481. doi: 10.7759/cureus.44481. eCollection 2023 Aug.
Ovarian tumors can be classified by their origin - epithelial tumors, germ cell tumors, and stromal tumors. Malignant struma ovarii (MSO) are 0.01% of all ovarian tumors. In order to be classified as a struma ovarii, more than 50% of the teratoma consists of thyroid tissue. The thyroid tissue in the struma ovarii exhibits the same histological and physiological properties as that of the cervical thyroid tissue. Poorly differentiated thyroid carcinoma (PDTC) is an extremely rare occurrence when arising from an MSO. Including this case report, there are only 10 reports of PDTC in the setting of MSO. Of these cases, this patient is the only one who presented with concurrent primary thyroid carcinoma (PTC). This case study examines how invaluable intra-professional collaboration is for appropriate diagnosis, along with attention to detail of identifying markers in pathology sections and use of the appropriate immunohistochemical analysis.
卵巢肿瘤可根据其起源进行分类——上皮性肿瘤、生殖细胞肿瘤和性索间质肿瘤。恶性卵巢甲状腺肿（MSO）占所有卵巢肿瘤的0.01%。为了被归类为卵巢甲状腺肿，畸胎瘤中超过50%由甲状腺组织组成。卵巢甲状腺肿中的甲状腺组织具有与颈部甲状腺组织相同的组织学和生理学特性。当起源于MSO时，低分化甲状腺癌（PDTC）极为罕见。包括本病例报告在内，仅有10例关于MSO合并PDTC的报道。在这些病例中，该患者是唯一同时患有原发性甲状腺癌（PTC）的。本病例研究探讨了专业内协作对于准确诊断的重要性，以及在病理切片中识别标志物细节的关注和适当免疫组化分析的应用。
