Zhuang Zhijian, Chen Delang, Liang Zhichao, Zhang Shuangyang, Liu Zhenyang, Chen Wufan, Qi Li
School of Biomedical Engineering, Southern Medical University, 1023 Shatai Rd., Baiyun District, Guangzhou, Guangdong, 510515, China.
Guangdong Provincial Key Laboratory of Medical Image Processing, Southern Medical University, 1023 Shatai Rd., Baiyun District, Guangzhou, Guangdong, 510515, China.
Biomed Opt Express. 2023 Aug 10;14(9):4594-4608. doi: 10.1364/BOE.496812. eCollection 2023 Sep 1.
Endoscopic airway optical coherence tomography (OCT) is a non-invasive and high resolution imaging modality for the diagnosis and analysis of airway-related diseases. During OCT imaging of the upper airway, in order to reliably characterize its 3D structure, there is a need to automatically detect the airway lumen contour, correct rotational distortion and perform 3D airway reconstruction. Based on a long-range endoscopic OCT imaging system equipped with a magnetic tracker, we present a fully automatic framework to reconstruct the 3D upper airway model with correct bending anatomy. Our method includes an automatic segmentation method for the upper airway based on dynamic programming algorithm, an automatic initial rotation angle error correction method for the detected 2D airway lumen contour, and an anatomic bending method combined with the centerline detected from the magnetically tracked imaging probe. The proposed automatic reconstruction framework is validated on experimental datasets acquired from two healthy adults. The result shows that the proposed framework allows the full automation of 3D airway reconstruction from OCT images and thus reveals its potential to improve analysis efficiency of endoscopic OCT images.
内镜气道光学相干断层扫描(OCT)是一种用于诊断和分析气道相关疾病的非侵入性高分辨率成像方式。在上气道的OCT成像过程中,为了可靠地表征其三维结构,需要自动检测气道管腔轮廓、校正旋转畸变并进行三维气道重建。基于配备磁跟踪器的远程内镜OCT成像系统,我们提出了一个全自动框架,以重建具有正确弯曲解剖结构的三维上气道模型。我们的方法包括基于动态规划算法的上气道自动分割方法、对检测到的二维气道管腔轮廓的自动初始旋转角度误差校正方法,以及结合从磁跟踪成像探头检测到的中心线的解剖弯曲方法。所提出的自动重建框架在从两名健康成年人获取的实验数据集上得到了验证。结果表明,所提出的框架允许从OCT图像中完全自动化三维气道重建,从而揭示了其提高内镜OCT图像分析效率的潜力。