Harris B, Young J, Hughes B
Br J Psychiatry. 1986 May;148:590-2. doi: 10.1192/bjp.148.5.590.
Appetite, weight, and preference for carbohydrate-containing food were followed in patients treated in double-blind trials of seven antidepressant regimes. Trimipramine and isocarboxazid combined had a significant effect in increasing appetite, carbohydrate preference, and weight; in patients who had lost appetite at presentation and were on this treatment, improvement in Hamilton score was linked to increase in weight--a finding not true of the other treatments.
在七项抗抑郁治疗方案的双盲试验中,对患者的食欲、体重以及对含碳水化合物食物的偏好进行了跟踪研究。曲米帕明和异卡波肼联合使用在增加食欲、碳水化合物偏好和体重方面具有显著效果;在就诊时食欲不振且接受该治疗的患者中,汉密尔顿评分的改善与体重增加有关——其他治疗则并非如此。