Polusny Melissa A, Marquardt Craig A, Hubbling Michelle, Campbell Emily Hagel, Arbisi Paul A, Davenport Nicholas D, Lim Kelvin O, Lissek Shmuel, Schaefer Jonathan D, Sponheim Scott R, Masten Ann S, Noorbaloochi Siamak
Minneapolis Veterans Affairs Health Care System, Minneapolis, MN, United States.
Center for Care Delivery and Outcomes Research, Minneapolis, MN, United States.
JMIR Res Protoc. 2023 Oct 4;12:e51235. doi: 10.2196/51235.
Military services provide a unique opportunity for studying resilience, a dynamic process of successful adaptation (ie, doing well in terms of functioning and symptoms) in response to significant adversity. Despite the tremendous interest in positive adaptation among military service members, little is known about the processes underlying their resilience. Understanding the neurobiological, cognitive, and social mechanisms underlying adaptive functioning following military stressor exposure is essential for enhancing the resilience of military service members.
The primary objective of the Advancing Research on Mechanisms of Resilience (ARMOR) longitudinal study is to characterize the trajectories of positive adaptation among young military recruits in response to basic combat training (BCT), a well-defined, uniform, and 10-week period of intense stress (aim 1), and identify promotive and protective processes contributing to individual variations in resilience (aim 2). The secondary objective is to investigate the pathways by which neurobehavioral markers of self-regulation assessed using electroencephalography and magnetic resonance imaging contribute to adaptive trajectories (aim 3).
ARMOR is an ongoing, prospective longitudinal cohort study of young military recruits who recently joined the National Guard but have not yet shipped out for BCT. Participants (N=1201) are assessed at 5 time points over the initial >2 years of military service beginning before BCT (baseline) and followed up at 2 weeks and 6, 12, and 18 months after BCT. Participants complete web-based questionnaires assessing vulnerability and protective factors, mental health, and socioemotional functioning at each time point and a battery of neurocognitive tests at time 0. A subset of participants also complete structured diagnostic interviews and additional self-report measures and perform neurobehavioral tasks before and after BCT during electroencephalography sessions and before BCT only during magnetic resonance imaging sessions.
This UG3/UH3 project was initially funded in August 2017, with the UG3 pilot work completed at the end of 2018. The UH3 phase of the project was funded in March 2019. Study enrollment for the UH3 phase began on April 14, 2019, and ended on October 16, 2021. A total of 1201 participants are enrolled in the study. Follow-up data collection for the UH3 phase is ongoing and projected to continue through February 2024. We will disseminate the findings through conferences, webinars, open access publications, and communications with participants and stakeholders.
The ARMOR study provides a rich data set to identify the predictors and mechanisms of resilient and nonresilient outcomes in the context of military stressors, which are intended to empirically inform the development of prevention and intervention strategies to enhance the resilience of military trainees and potentially other young people facing significant life challenges.
INTERNATIONAL REGISTERED REPORT IDENTIFIER (IRRID): DERR1-10.2196/51235.
军事服役为研究复原力提供了独特机会,复原力是一个在面对重大逆境时成功适应(即在功能和症状方面表现良好)的动态过程。尽管军事服役人员对积极适应有着极大兴趣,但对其复原力背后的过程却知之甚少。了解军事应激源暴露后适应性功能背后的神经生物学、认知和社会机制对于增强军事服役人员的复原力至关重要。
推进复原力机制研究(ARMOR)纵向研究的主要目的是描绘年轻新兵在应对基础战斗训练(BCT)时积极适应的轨迹,基础战斗训练是一个明确、统一且为期10周的高强度应激期(目标1),并确定导致复原力个体差异的促进和保护过程(目标2)。次要目的是研究使用脑电图和磁共振成像评估的自我调节神经行为标志物促成适应性轨迹的途径(目标3)。
ARMOR是一项正在进行的前瞻性纵向队列研究,研究对象是最近加入国民警卫队但尚未前往参加基础战斗训练的年轻新兵。参与者(N = 1201)在军事服役的最初2年多时间里的5个时间点接受评估,评估从基础战斗训练前(基线)开始,在基础战斗训练后2周、6个月、12个月和18个月进行随访。参与者在每个时间点完成基于网络的问卷,评估脆弱性和保护因素、心理健康和社会情感功能,并在时间点0完成一系列神经认知测试。一部分参与者还在脑电图检查期间基础战斗训练前后以及仅在磁共振成像检查期间基础战斗训练前完成结构化诊断访谈和额外的自我报告测量,并执行神经行为任务。
这个UG3/UH3项目于最初于2017年8月获得资助,UG3试点工作于2018年底完成。该项目的UH3阶段于2019年3月获得资助。UH3阶段的研究招募于2019年4月14日开始,并于2021年10月16日结束。共有1201名参与者被纳入该研究。UH3阶段的随访数据收集正在进行中,预计将持续到2024年2月。我们将通过会议、网络研讨会、开放获取出版物以及与参与者和利益相关者的沟通来传播研究结果。
ARMOR研究提供了丰富的数据集,以确定军事应激源背景下复原和非复原结果的预测因素和机制,旨在为制定预防和干预策略提供实证依据,以增强军事受训人员以及可能面临重大生活挑战的其他年轻人的复原力。
国际注册报告识别码(IRRID):DERR1 - 10.2196/51235。