Vanderbilt University Institute of Imaging Science, Vanderbilt University Medical Center, Nashville, TN, USA.
Department of Biomedical Engineering, Vanderbilt University, Nashville, TN, USA.
J Appl Biomech. 2023 Oct 4;39(6):421-431. doi: 10.1123/jab.2022-0270. Print 2023 Dec 1.
A muscle's architecture, defined as the geometric arrangement of its fibers with respect to its mechanical line of action, impacts its abilities to produce force and shorten or lengthen under load. Ultrasound and other noninvasive imaging methods have contributed significantly to our understanding of these structure-function relationships. The goal of this work was to develop a MATLAB toolbox for tracking and mathematically representing muscle architecture at the fascicle scale, based on brightness-mode ultrasound imaging data. The MuscleUS_Toolbox allows user-performed segmentation of a region of interest and automated modeling of local fascicle orientation; calculation of streamlines between aponeuroses of origin and insertion; and quantification of fascicle length, pennation angle, and curvature. A method is described for optimizing the fascicle orientation modeling process, and the capabilities of the toolbox for quantifying and visualizing fascicle architecture are illustrated in the human tibialis anterior muscle. The toolbox is freely available.
肌肉的结构，定义为其纤维相对于其力学作用线的几何排列，影响其在负载下产生力和缩短或伸长的能力。超声和其他非侵入性成像方法极大地促进了我们对这些结构-功能关系的理解。这项工作的目的是开发一个基于亮度模式超声成像数据的 MATLAB 工具箱，用于跟踪和数学表示肌纤维结构。MuscleUS_Toolbox 允许用户对感兴趣区域进行分段，并自动对局部肌纤维方向进行建模；计算起点和止点腱膜之间的流线；以及量化肌纤维长度、肌纤维角度和曲率。描述了一种优化肌纤维方向建模过程的方法，并说明了该工具在量化和可视化肌纤维结构方面的功能，以人类胫骨前肌为例。该工具箱是免费提供的。
