Institute for Behavioral Genetics and the Department of Integrative Physiology, University of Colorado, Boulder, Colorado, USA.
Genes Brain Behav. 2023 Oct;22(5):e12866. doi: 10.1111/gbb.12866. Epub 2023 Sep 19.
This issue contains a series of articles describing the various resources, studies, results, and future directions for the collaborative study on the genetics of alcoholism (COGA). The collaborative and integrative approach initiated by this group ~30 years ago serves as an excellent example of the strength of team science. Individually, various aspects of COGA would be limited in their impact toward improved understanding of alcohol use disorder. Collectively, their wholistic approach which spans deep longitudinal phenotypic assessments in families to include the application of large-scale omics technologies and cell-culture based molecular studies has demonstrated the power of working together.
本期特刊载有一系列文章，介绍酗酒遗传学协作研究（COGA）的各种资源、研究、成果及未来方向。该研究组于约 30 年前开创了这种协作和综合的方法，堪称团队科学优势的一个绝佳范例。COGA 的各个方面如果各自为战，其影响可能会局限于增进对酒精使用障碍的理解。但它们采取的整体方法将家庭中的深度纵向表型评估与大规模组学技术和基于细胞培养的分子研究结合起来，已经显示出了合作的力量。
