Department of Biochemistry and Molecular Biology, Indiana University School of Medicine, 635 Barnhill Drive, Indianapolis, IN, USA.
BMC Genet. 2005 Dec 30;6 Suppl 1(Suppl 1):S2. doi: 10.1186/1471-2156-6-S1-S2.
The data provided to the Genetic Analysis Workshop 14 (GAW 14) was the result of a collaboration among several different groups, catalyzed by Elizabeth Pugh from The Center for Inherited Disease Research (CIDR) and the organizers of GAW 14, Jean MacCluer and Laura Almasy. The DNA, phenotypic characterization, and microsatellite genomic survey were provided by the Collaborative Study on the Genetics of Alcoholism (COGA), a nine-site national collaboration funded by the National Institute of Alcohol and Alcoholism (NIAAA) and the National Institute of Drug Abuse (NIDA) with the overarching goal of identifying and characterizing genes that affect the susceptibility to develop alcohol dependence and related phenotypes. CIDR, Affymetrix, and Illumina provided single-nucleotide polymorphism genotyping of a large subset of the COGA subjects. This article briefly describes the dataset that was provided.
提供给遗传分析工作坊 14（GAW 14）的数据是由多个不同小组合作的结果，由伊丽莎白·普格（Elizabeth Pugh）从遗传性疾病研究中心（CIDR）以及 GAW 14 的组织者吉恩·麦克卢尔（Jean MacCluer）和劳拉·阿玛西（Laura Almasy）推动。DNA、表型特征和微卫星基因组调查由酒精中毒遗传学合作研究（COGA）提供，这是一个由国家酒精滥用与酒精中毒研究所（NIAAA）和国家药物滥用研究所（NIDA）资助的九个地点的全国性合作，其总体目标是确定和描述影响易感性的基因，从而导致酒精依赖和相关表型。CIDR、Affymetrix 和 Illumina 为 COGA 的大部分受试者提供了单核苷酸多态性基因分型。本文简要描述了提供的数据集。
