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双胎妊娠与围产期结局的相关性及早产影响的回顾性研究

Retrospective Study of the Correlation Between Twin Pregnancies and Perinatal Outcome in Association to the Impact of Preterm Birth.

作者信息

Michalopoulos Spyridon, Tsikouras Panagiotis, Varlami Vassiliki, Lambrinos Dimitrios, Bothou Anastasia, Nikolettos Konstantinos, Papanikolopoulou Stavroula, Marinos Georgios, Iatrakis Georgios, Nikolettos Nikolaos

机构信息

Department of Obstetrics and Gynecology, Democritus Univesity of Thrace, Greece.

Neonatal Intensive Care Unit of University Hospital Alexandroupolis, Greece.

出版信息

Mater Sociomed. 2023 Sep;35(3):215-221. doi: 10.5455/msm.2023.35.215-221.

Abstract

BACKGROUND

Twin pregnancies make up 2% to 4% of all births. Incidence of spontaneous twin pregnancies varies around the world, with percentages ranging from 8/1000 to >17/1000 births. The variation in twin pregnancy rates is thought to be due to dizygotic pregnancies, since monozygotic pregnancies have a consistent incidence of 3.5/1000 to 4/1000 births. The incidence of twin pregnancies after the widespread use of assisted reproduction has increased significantly.

OBJECTIVE

The purpose of the present study is to investigate factors , who contribute to improve the perinatal outcome in twin pregnancies. Support will be provided by the results of twin pregnancies by the Department of Obstetrics and Gynaecology of Demokrition University of Thrace (Alexandroupolis, Greece) in the last fifteen years.

METHODS

From the above Department, data were collected on the number of twin pregnancies, maternal age, gestational age, mode of delivery (spontaneous delivery or caesarean section), birth weight and rate of twin pregnancies with assisted reproduction.

RESULTS

The results showed the increasing trend of twin pregnancies and births. A total of 304 twin pregnancies were identified (rate 2.75%). The rate of assisted reproduction was 34.83% in our sample, while the rate of cesarean deliveries was 95.5%, showing a large increase in recent years. In ten cases, normal delivery was successfully performed. The gestational age in twin pregnancies that ended with normal delivery was 37.37 + 3 weeks and the fetuses were both cephalic presentations. The main reason for admission of newborns to the NICU Department was prematurity.

CONCLUSION

The constantly improving education of perinatalists and understanding of the pathophysiology may lead to individualization of their treatment, and improvement of their prognosis based on recent scientific data from other international centers.

摘要

背景

双胎妊娠占所有分娩的2%至4%。自然双胎妊娠的发生率在世界各地有所不同,每1000例分娩中的发生率从8例到超过17例不等。双胎妊娠率的差异被认为是由于双卵双胎妊娠,因为单卵双胎妊娠的发生率始终为每1000例分娩中有3.5例至4例。辅助生殖广泛应用后,双胎妊娠的发生率显著增加。

目的

本研究的目的是调查有助于改善双胎妊娠围产期结局的因素。希腊德拉马蒂亚大学(亚历山德鲁波利斯)妇产科过去十五年的双胎妊娠结果将提供支持。

方法

从上述科室收集了双胎妊娠数量、产妇年龄、孕周、分娩方式(顺产或剖宫产)、出生体重以及辅助生殖双胎妊娠率的数据。

结果

结果显示双胎妊娠和分娩呈上升趋势。共确定了304例双胎妊娠(发生率为2.75%)。我们样本中的辅助生殖率为34.83%,而剖宫产率为95.5%,显示近年来大幅上升。有10例成功进行了顺产。顺产结束的双胎妊娠孕周为37.37 + 3周,胎儿均为头先露。新生儿入住新生儿重症监护室的主要原因是早产。

结论

围产医学专家的教育水平不断提高以及对病理生理学的理解可能会导致治疗个体化,并根据其他国际中心的最新科学数据改善其预后。

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Prevention of preterm birth in twin pregnancies.双胎妊娠的早产预防。
Am J Obstet Gynecol MFM. 2022 Mar;4(2S):100551. doi: 10.1016/j.ajogmf.2021.100551. Epub 2021 Dec 8.

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