妊娠合并未达可存活孕周的早产和胎膜早破的管理：新生儿存活极限如何？——一篇综述
The Management of Pregnancy Complicated with the Previable Preterm and Preterm Premature Rupture of the Membranes: What about a Limit of Neonatal Viability?-A Review.
作者信息
Feduniw Stepan, Gaca Zuzanna, Malinowska Olga, Brunets Weronika, Zgliczyńska Magdalena, Włodarczyk Marta, Wójcikiewicz Anna, Ciebiera Michał
机构信息
Department of Reproductive Health, Centre of Postgraduate Medical Education, 01-004 Warsaw, Poland.
Czerniakowski Hospital, 00-739 Warsaw, Poland.
出版信息
Diagnostics (Basel). 2022 Aug 22;12(8):2025. doi: 10.3390/diagnostics12082025.
Abstract
Preterm premature rupture of the membranes (PPROM) at the limit of viability is associated with low neonatal survival rates and a high rate of neonatal complications in survivors. It carries a major risk of maternal morbidity and mortality. The limit of viability can be defined as the earliest stage of fetal maturity when a fetus has a reasonable chance, although not a high likelihood, for extra-uterine survival. The study reviews available data on preventing preterm delivery caused by the previable PPROM, pregnancy latency, therapeutic options including the use of antibiotics and steroids, neonatal outcomes, and future directions and opportunities.
摘要
孕龄极限时的胎膜早破（PPROM）与新生儿低存活率以及存活者中高比例的新生儿并发症相关。它还存在孕产妇发病和死亡的重大风险。孕龄极限可定义为胎儿成熟的最早阶段，此时胎儿虽宫外存活可能性不高，但有合理机会存活。本研究回顾了关于预防孕龄极限前PPROM所致早产、妊娠潜伏期、包括使用抗生素和类固醇在内的治疗选择、新生儿结局以及未来方向和机会的现有数据。
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