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非洲的个性化医疗:现状、进展与挑战。

Personalizing medicine in Africa: current state, progress and challenges.

作者信息

Owolabi Paul, Adam Yagoub, Adebiyi Ezekiel

机构信息

Covenant Applied Informatics and Communication, Africa Centre of Excellence (CApIC-ACE), Covenant University, Ota, Ogun State, Nigeria.

Department of Computer and Information Science, Covenant University, Ota, Ogun State, Nigeria.

出版信息

Front Genet. 2023 Sep 19;14:1233338. doi: 10.3389/fgene.2023.1233338. eCollection 2023.

Abstract

Personalized medicine has been identified as a powerful tool for addressing the myriad of health issues facing different health systems globally. Although recent studies have expanded our understanding of how different factors such as genetics and the environment play significant roles in affecting the health of individuals, there are still several other issues affecting their translation into personalizing health interventions globally. Since African populations have demonstrated huge genetic diversity, there is a significant need to apply the concepts of personalized medicine to overcome various African-specific health challenges. Thus, we review the current state, progress, and challenges facing the adoption of personalized medicine in Africa with a view to providing insights to critical stakeholders on the right approach to deploy.

摘要

个性化医疗已被视为应对全球不同卫生系统所面临的众多健康问题的有力工具。尽管最近的研究扩展了我们对诸如基因和环境等不同因素如何在影响个体健康方面发挥重要作用的理解,但在将这些因素转化为全球个性化健康干预措施方面,仍存在其他若干问题。由于非洲人群表现出巨大的遗传多样性,因此迫切需要应用个性化医疗的概念来克服各种非洲特有的健康挑战。因此,我们回顾了非洲采用个性化医疗的现状、进展和挑战,以期为关键利益相关者提供关于正确部署方法的见解。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/20af/10546210/aacf7610f3ca/fgene-14-1233338-g001.jpg

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