Selcuk University Department of Orthopedics and Traumatology, Hand Surgery Department Akademi Mahallesi, Celal Bayar Cd. No:313, 42130 Selçuklu/Konya, Turkey.
Selcuk University Department of Orthopedics and Traumatology, Akademi Mahallesi, Celal Bayar Cd. No:313, 42130 Selçuklu/Konya, Turkey.
Hand Surg Rehabil. 2024 Feb;43(1):101604. doi: 10.1016/j.hansur.2023.09.371. Epub 2023 Oct 4.
We aimed to evaluate the effect of botulinum neurotoxin type-A (Btx-A) injection into the pronator teres muscle in proximal median nerve entrapment (PMNE).
Intramuscular injection of 30 IU Btx-A into the pronator teres muscle was performed in 12 patients (14 extremities) diagnosed with PMNE. The injection was made under nerve stimulator control. One patient with thoracic outlet syndrome was excluded from the study and not included in the clinical evaluation. Grip and pinch strength, 2-point discrimination, Q-DASH score, and pain on VAS were evaluated and compared before and 6-8 months after injection. The patients were contacted again by phone after the first and fifth years and asked about PMNE symptomatology.
None of the patients had complications. No significant difference in pinch strength was observed following Btx-A injection, but there was significant improvement in grip strength, 2-point discrimination, and Q-DASH and VAS pain scores.
The outcomes of our study were promising: Btx-A injection improved symptoms in patients with PMNE.
Level IV.
评估在正中神经近端卡压（PMNE）中，将肉毒杆菌神经毒素 A 型（Btx-A）注射到旋前圆肌中的效果。
对 12 名（14 侧肢体）被诊断为 PMNE 的患者，在神经刺激器的控制下，将 30IU 的 Btx-A 注射到旋前圆肌中。一名患有胸廓出口综合征的患者被排除在研究之外，并未纳入临床评估。在注射前和注射后 6-8 个月，评估并比较握力和捏力、两点辨别觉、Q-DASH 评分和 VAS 疼痛评分。在第 1 年和第 5 年，通过电话再次联系患者，询问 PMNE 症状。
所有患者均无并发症。Btx-A 注射后，捏力无显著差异，但握力、两点辨别觉、Q-DASH 和 VAS 疼痛评分均显著改善。
我们的研究结果很有前景：Btx-A 注射改善了 PMNE 患者的症状。
IV 级。
