Department of Clinical Microbiology, İstanbul University of Health Sciences, Mehmet Akif Ersoy Thoracic Cardiovascular Surgery Training and Research Hospital, İstanbul, Türkiye.
Department of Rare Diseases, İstanbul University, Institute of Health Sciences, İstanbul, Türkiye.
Anatol J Cardiol. 2023 Dec 1;27(12):706-711. doi: 10.14744/AnatolJCardiol.2023.3431. Epub 2023 Oct 6.
The severe acute respiratory syndrome coronavirus 2 is the source of the global pandemic known as coronavirus disease 2019, and the disease prognosis is also linked to the prevalence of cardiac problems. In our study, we aimed to contribute to the early diagnosis and treatment of cardiac complications by evaluating ischemic modified albumin levels in adults with coronavirus disease 2019 disease.
Our study was conducted with a total of 176 cases: group 1 (n = 70) with cardiac injury and coronavirus disease 2019 (+), group 2 (n = 57) with cardiac injury and coronavirus disease (-), and group 3 (n = 49) with healthy volunteers. The Mann-Whitney U test, the average, SD, minimum and maximum values, intergroup comparison of the results, and statistical significance were evaluated with the Pearson correlation coefficient.
As a result of the bilateral comparisons, ischemic modified albumin measurements of the coronavirus disease 2019 (+) and coronavirus disease 2019 (-) groups were higher than the control group (P =.006 and P =.006, respectively). There was no statistically significant difference between ischemic modified albumin measurements of coronavirus disease 2019 (+) and coronavirus disease 2019 (-) groups.
Ischemic modified albumin measurement accelerates the diagnosis and treatment process in the evaluation of cardiac injuries in coronavirus disease 2019 patients.
严重急性呼吸综合征冠状病毒 2 是导致全球 2019 年冠状病毒病大流行的源头，疾病预后也与心脏问题的流行有关。在我们的研究中，我们旨在通过评估成人 2019 年冠状病毒病患者的缺血修饰白蛋白水平，为心脏并发症的早期诊断和治疗做出贡献。
我们的研究共纳入了 176 例病例：第 1 组（n = 70）为伴有心脏损伤和 2019 年冠状病毒病（+）的患者，第 2 组（n = 57）为伴有心脏损伤和 2019 年冠状病毒病（-）的患者，第 3 组（n = 49）为健康志愿者。采用曼-惠特尼 U 检验、平均值、标准差、最小值和最大值、结果的组间比较以及皮尔逊相关系数评估统计显著性。
双侧比较结果显示，2019 年冠状病毒病（+）组和 2019 年冠状病毒病（-）组的缺血修饰白蛋白测量值均高于对照组（分别为 P =.006 和 P =.006）。2019 年冠状病毒病（+）组和 2019 年冠状病毒病（-）组的缺血修饰白蛋白测量值之间无统计学差异。
缺血修饰白蛋白测量值可加速 2019 年冠状病毒病患者心脏损伤评估的诊断和治疗过程。
