Braun L
Dtsch Med Wochenschr. 1986 Dec 5;111(49):1869-73. doi: 10.1055/s-2008-1068727.
A comparison of 149 patients aged over 80 years with a group of 49 under 50 years demonstrated that colorectal carcinoma is more frequent in older persons and more frequently in the right and middle third of the colon. Ileus and perforation are more common in the elderly and are usually diagnosed at a more advanced stage making curative surgery less likely. Perioperative mortality in the over-80s totalled 18.8%. Re-operations had to be performed in 4.7%, an external stoma was needed in 28.1%. Postoperative complications occurred in 25.5% of the older age group, compared with 16.3% in the under-50s. Five-year survival rate was 19.1% in the over-80s. The late mortality rate was 36.2% in the older and 30.0% in the younger age group, after an average postoperative period of 14 and 21.1 months, respectively. Treatment results even in the higher age groups can be improved by earlier diagnosis and treatment.
对149名80岁以上的患者与49名50岁以下的患者进行比较，结果表明，结直肠癌在老年人中更为常见，且在结肠右半段和中段更为频发。肠梗阻和穿孔在老年人中更为常见，且通常在疾病更晚期才被诊断出来，这使得根治性手术的可能性降低。80岁以上患者的围手术期死亡率总计为18.8%。4.7%的患者需要再次手术，28.1%的患者需要造口。老年组术后并发症发生率为25.5%，而50岁以下组为16.3%。80岁以上患者的五年生存率为19.1%。在术后平均14个月和21.1个月后，老年组的晚期死亡率为36.2%，年轻组为30.0%。通过早期诊断和治疗，即使是较高年龄组的治疗效果也可以得到改善。
