Department of Anatomy, Faculty of Basic Medical Sciences, Edo State University Uzairue, Edo State, Nigeria.
Department of Pharmacognosy, Faculty of Pharmacy, College of Medicine, University of Lagos, Lagos State, Nigeria.
J Trace Elem Med Biol. 2023 Dec;80:127311. doi: 10.1016/j.jtemb.2023.127311. Epub 2023 Sep 23.
Chrysophyllum albidum, also known as Africa star apple, has so many ethnobotanical uses in African healing system. Thus, a study that reveals possible trace elements and its phytochemical profile will give an essential insight to the bioactivity profile of the plant. The study was to identify the trace elements and the bioactive compounds present in Chrysophyllum albidum (C. albidum) leaf extract MATERIALS AND METHODS: The ethanol leaf extract of Chrysophyllum albidum was evaluated for trace elements using an Atomic Absorption Spectrophotometry (ASS) while the chemical composition was analysed using Gas Chromatography-Mass Spectrometry (GC/MS). The identification of phytoconstituents using GC/MS was based on the instrument library, peak area and retention time.
The ethanol leaf extract of C. albidum showed a high content of potassium, calcium, magnesium and sodium, while relative low content of manganese, iron, copper, zinc, lead and nickel. Total of 30 peaks representing 30 identified compounds were recorded in the GC/MS analysis. These include a variety of heterocyclic compounds such as fatty acids, organic compounds, esters, and disaccharides etc. The major constituents of the extract were: Sucrose (37.45%), followed by 1,2,3-Propanetriol,1-acetate (7.86%), di-Glyceraldehyde dimer (5.70%), 1-(3-Benzyl-2-thioureido)-1-deoxy-beta-d glucopyranose 2,3,4,6-tetraacetate (4.53%), 4 H-Pyran-4-one, 2,3-dihydro-3, 5-dihydroxy-6-methyl- (4.49%), 3-Deoxy-d-Mannoic lactone (3.14%), Glycerine (3.04%) and minor compounds that are less than 3%.
The elemental composition of the leaf extract of C. albidum may be influenced by the environmental factors such as soil composition surrounding the plant's roots, while a variety of bioactive compounds with diverse biological activities were present. Hence, the plant have a potential pharmacological activities.
非洲星苹果（Chrysophyllum albidum），又称非洲星苹果，在非洲传统医学系统中有许多民族植物学用途。因此，研究揭示其可能存在的微量元素及其植物化学成分将为植物的生物活性特征提供重要的见解。本研究旨在鉴定非洲星苹果（C. albidum）叶提取物中的微量元素和生物活性化合物。
采用原子吸收分光光度法（ASS）评估非洲星苹果叶乙醇提取物中的微量元素，同时采用气相色谱-质谱联用（GC/MS）分析其化学成分。使用 GC/MS 鉴定植物成分的依据是仪器库、峰面积和保留时间。
C. albidum 乙醇叶提取物显示出钾、钙、镁和钠的高含量，而锰、铁、铜、锌、铅和镍的含量相对较低。GC/MS 分析共记录了 30 个峰，代表 30 种鉴定化合物。这些包括各种杂环化合物，如脂肪酸、有机化合物、酯和二糖等。提取物的主要成分是：蔗糖（37.45%），其次是 1,2,3-丙三醇 1-醋酸酯（7.86%）、二甘油醛二聚体（5.70%）、1-（3-苄基-2-硫脲基）-1-脱氧-β-d-吡喃葡萄糖 2,3,4,6-四乙酸酯（4.53%）、4H-吡喃-4-酮、2,3-二氢-3,5-二羟基-6-甲基-（4.49%）、3-脱氧-d-甘露酸内酯（3.14%）、甘油（3.04%）和含量小于 3%的少量化合物。
C. albidum 叶提取物的元素组成可能受植物根系周围土壤成分等环境因素的影响，而存在多种具有不同生物活性的生物活性化合物。因此，该植物具有潜在的药理学活性。
