丹参酮IIA修复脊髓损伤的可能治疗机制。
Possible mechanisms of treatment for spinal cord injury repair with tanshinone IIA.
作者信息
Jia Zhiwei, Wen Tianlin, Zhang Yuning
机构信息
Department of Orthopaedics, Dongzhimen Hospital, Beijing University of Chinese Medicine, Beijing, China.
Class 6 of Year 2021 Clinical Medicine, School of Medicine, Shenzhen University, Shenzhen, Guangdong Province, China.
出版信息
Front Mol Neurosci. 2023 Sep 21;16:1277755. doi: 10.3389/fnmol.2023.1277755. eCollection 2023.
Tanshinone IIA serves as a coenzyme for certain biochemical reactions, exhibiting various pharmacological effects in the treatment of neurological diseases including spinal cord injury (SCI), however, its working mechanism in the treatment of SCI is not clear. Based on previous research, we believe that tanshinone IIA promotes the survival and repair of nerves after spinal cord injury through its pharmacological effects such as anti-inflammatory, antioxidant, and prevention of cellular apoptosis in the spinal cord.
丹参酮IIA作为某些生化反应的辅酶，在治疗包括脊髓损伤（SCI）在内的神经疾病中表现出多种药理作用，然而，其治疗SCI的作用机制尚不清楚。基于先前的研究，我们认为丹参酮IIA通过其抗炎、抗氧化和预防脊髓细胞凋亡等药理作用促进脊髓损伤后神经的存活和修复。
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