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An important resource and analytic platform for human and mouse cardiovascular-related -regulatory elements.用于人类和小鼠心血管相关调控元件的重要资源和分析平台。
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-Cardio: A comprehensive analysis platform for cardiovascular-relavant regulation in human and mouse.-心脏：一个用于人类和小鼠心血管相关调节的综合分析平台。
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Synthetic and genomic regulatory elements reveal aspects of -regulatory grammar in mouse embryonic stem cells.合成和基因组调控元件揭示了小鼠胚胎干细胞中 - 调控语法的某些方面。
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Identification and Conservation Analysis of -Regulatory Elements in Pig Liver.猪肝脏中 - 调控元件的鉴定和保护分析。
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A map of cis-regulatory modules and constituent transcription factor binding sites in 80% of the mouse genome.在 80%的小鼠基因组中顺式调控模块和组成转录因子结合位点的图谱。
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DNase I hypersensitivity analysis of the mouse brain and retina identifies region-specific regulatory elements.小鼠大脑和视网膜的DNA酶I超敏反应分析确定了区域特异性调控元件。
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Single-cell chromatin accessibility and transcriptome atlas of mouse embryos.小鼠胚胎的单细胞染色质可及性和转录组图谱
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A map of the cis-regulatory sequences in the mouse genome.小鼠基因组中顺式调控序列的图谱。
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本文引用的文献

1
-Cardio: A comprehensive analysis platform for cardiovascular-relavant regulation in human and mouse.-心脏：一个用于人类和小鼠心血管相关调节的综合分析平台。
Mol Ther Nucleic Acids. 2023 Jul 27;33:655-667. doi: 10.1016/j.omtn.2023.07.030. eCollection 2023 Sep 12.
2
Single-nucleus chromatin accessibility profiling highlights regulatory mechanisms of coronary artery disease risk.单细胞染色质可及性分析凸显冠状动脉疾病风险的调控机制。
Nat Genet. 2022 Jun;54(6):804-816. doi: 10.1038/s41588-022-01069-0. Epub 2022 May 19.
3
PCRMS: a database of predicted cis-regulatory modules and constituent transcription factor binding sites in genomes.PCRMS：基因组中预测的顺式调控模块和组成转录因子结合位点数据库。
Database (Oxford). 2022 Apr 22;2022. doi: 10.1093/database/baac024.
4
ReMap 2022: a database of Human, Mouse, Drosophila and Arabidopsis regulatory regions from an integrative analysis of DNA-binding sequencing experiments.ReMap 2022：一个整合了 DNA 结合测序实验分析的人类、小鼠、果蝇和拟南芥调控区域数据库。
Nucleic Acids Res. 2022 Jan 7;50(D1):D316-D325. doi: 10.1093/nar/gkab996.
5
Cardiac cell type-specific gene regulatory programs and disease risk association.心脏细胞类型特异性基因调控程序与疾病风险关联。
Sci Adv. 2021 May 14;7(20). doi: 10.1126/sciadv.abf1444. Print 2021 May.
6
FootprintDB: Analysis of Plant Cis-Regulatory Elements, Transcription Factors, and Binding Interfaces.足迹数据库：植物顺式作用调控元件、转录因子及结合界面分析
Methods Mol Biol. 2016;1482:259-77. doi: 10.1007/978-1-4939-6396-6_17.
7
Identification of altered cis-regulatory elements in human disease.鉴定人类疾病中改变的顺式调控元件。
Trends Genet. 2015 Feb;31(2):67-76. doi: 10.1016/j.tig.2014.12.003. Epub 2015 Jan 27.
8
Cis-regulatory elements and human evolution.顺式调控元件与人类进化
Curr Opin Genet Dev. 2014 Dec;29:81-9. doi: 10.1016/j.gde.2014.08.011. Epub 2014 Sep 16.
9
PreCisIon: PREdiction of CIS-regulatory elements improved by gene's positION.精确性：通过基因位置提高 CIS 调控元件的预测。
Nucleic Acids Res. 2013 Feb 1;41(3):1406-15. doi: 10.1093/nar/gks1286. Epub 2012 Dec 14.
10
TRED: a Transcriptional Regulatory Element Database and a platform for in silico gene regulation studies.TRED：一个转录调控元件数据库以及用于计算机基因调控研究的平台。
Nucleic Acids Res. 2005 Jan 1;33(Database issue):D103-7. doi: 10.1093/nar/gki004.

An important resource and analytic platform for human and mouse cardiovascular-related -regulatory elements.

作者信息

Xie Longxiang, Wu Shengnan, Guo Xiangqian

机构信息

Institute of Biomedical Informatics, Bioinformatics Center, Henan Provincial Engineering Center for Tumor Molecular Medicine, Academy for Advanced Interdisciplinary Studies, School of Basic Medical Sciences, Henan University, Kaifeng, Henan 475004, China.

出版信息

Mol Ther Nucleic Acids. 2023 Sep 28;34:102033. doi: 10.1016/j.omtn.2023.102033. eCollection 2023 Dec 12.

DOI:10.1016/j.omtn.2023.102033
PMID:37808923
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10556829/
Abstract
摘要