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持续的视力丧失:肺炎克雷伯菌的毒力

Unrelenting Vision Loss: The Virulence of Klebsiella pneumoniae.

作者信息

Prasad Minali, Kosowsky Tova, Chen Xuejing, Davoudi Moghaddam Samaneh, Ness Steven, Peeler Crandall, Siegel Nicole H, Subramanian Manju L

机构信息

Ophthalmology, Boston University Chobanian & Avedisian School of Medicine, Boston, USA.

Ophthalmology, Boston Medical Center, Boston, USA.

出版信息

Cureus. 2023 Sep 6;15(9):e44786. doi: 10.7759/cureus.44786. eCollection 2023 Sep.

DOI:10.7759/cureus.44786
PMID:37809162
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10558182/
Abstract

A 37-year-old Hispanic male with a recent history of COVID-19 infection and type 2 diabetes mellitus was admitted to the hospital with shortness of breath, chest pain, and hyperglycemia. Eye exam and imaging findings indicated endogenous endophthalmitis confirmed by blood cultures that speciated to . The patient's eye condition progressed, ultimately resulting in no light perception less than a month after the initial evaluation. Due to the rapidly progressive nature of Klebsiella endogenous endophthalmitis, we recommend that primary teams consult ophthalmology for close monitoring of patients with a high index of suspicion.

摘要

一名37岁的西班牙裔男性,近期有新冠病毒感染史和2型糖尿病,因呼吸急促、胸痛和高血糖入院。眼科检查和影像学检查结果提示内源性眼内炎,血培养确诊为 。患者的眼部病情进展,在初次评估后不到一个月最终导致无光感。由于肺炎克雷伯菌内源性眼内炎的快速进展特性,我们建议初级医疗团队咨询眼科,以便对高度怀疑的患者进行密切监测。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6e26/10558182/7f5381703d18/cureus-0015-00000044786-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6e26/10558182/529254ce87ae/cureus-0015-00000044786-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6e26/10558182/bfc330bcd13a/cureus-0015-00000044786-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6e26/10558182/93ddf6eed06a/cureus-0015-00000044786-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6e26/10558182/7f5381703d18/cureus-0015-00000044786-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6e26/10558182/529254ce87ae/cureus-0015-00000044786-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6e26/10558182/bfc330bcd13a/cureus-0015-00000044786-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6e26/10558182/93ddf6eed06a/cureus-0015-00000044786-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6e26/10558182/7f5381703d18/cureus-0015-00000044786-i04.jpg

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本文引用的文献

1
Hypervirulent Endogenous Endophthalmitis-A Global Emerging Disease.高毒力内源性眼内炎——一种全球新出现的疾病
Life (Basel). 2021 Jul 10;11(7):676. doi: 10.3390/life11070676.
2
A global perspective on the convergence of hypervirulence and carbapenem resistance in Klebsiella pneumoniae.从全球视角看肺炎克雷伯菌的高毒力与碳青霉烯类耐药性的趋同。
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J Ophthalmol. 2020 Oct 23;2020:8869590. doi: 10.1155/2020/8869590. eCollection 2020.
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A Case of a Large Sub-retinal Abscess Secondary to Klebsiella pneumoniae Endophthalmitis in a Pyelonephritis Patient.一名肾盂肾炎患者继发肺炎克雷伯菌眼内炎后出现巨大视网膜下脓肿的病例。
Cureus. 2019 May 14;11(5):e4656. doi: 10.7759/cureus.4656.
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[Endogenous endophthalmitis associated with pneumonia: 3 cases report and literature review].[肺炎相关性内源性眼内炎:3例报告及文献复习]
Zhonghua Jie He He Hu Xi Za Zhi. 2019 Jun 12;42(6):438-443. doi: 10.3760/cma.j.issn.1001-0939.2019.06.007.
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Clin Exp Ophthalmol. 2017 Mar;45(2):135-142. doi: 10.1111/ceo.12827. Epub 2016 Sep 15.
8
Klebsiella pneumoniae liver abscess complicated by endogenous endophthalmitis: the importance of early diagnosis and intervention.肺炎克雷伯菌肝脓肿并发内源性眼内炎:早期诊断和干预的重要性
Med J Aust. 2015 Oct 5;203(7):300-1. doi: 10.5694/mja15.00107.
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Endophthalmitis.眼内炎。
Clin Microbiol Infect. 2013 Mar;19(3):227-34. doi: 10.1111/1469-0691.12118.
10
Risk factors for endogenous endophthalmitis secondary to klebsiella pneumoniae liver abscess: 20-year experience in Southern Taiwan.台湾南部 20 年经验:与克雷伯氏肺炎菌肝脓疡有关之内生性眼内炎之危险因子。
Retina. 2011 Nov;31(10):2026-31. doi: 10.1097/IAE.0b013e31820d3f9e.