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厄运降临:一份自传体病例报告

A Stroke of Bad Luck: An Autobiographical Case Report.

作者信息

Cohen Philip R

机构信息

Dermatology, University of California Davis Medical Center, Sacramento, USA.

出版信息

Cureus. 2023 Sep 6;15(9):e44788. doi: 10.7759/cureus.44788. eCollection 2023 Sep.

Abstract

Strokes are a common cause of death. Cardiovascular disease, including atrial fibrillation and atrial flutter, is a frequent cause of ischemic strokes. A 64-year-old man developed isolated dysarthria without any other neurologic manifestations as the presentation of an ischemic stroke resulting from occlusion to the middle cerebral artery and affecting the cortex supplied by the artery. He was discovered to be in atrial flutter which was determined to be the likely etiology of his stroke. He was hospitalized and anticoagulated with heparin; as an outpatient, his anticoagulation was maintained with the direct oral anticoagulant apixaban. Amiodarone was required to medically convert him to normal sinus rhythm; he has typical atrial flutter and is going to be evaluated for atrial flutter ablation. His dysarthria began to improve within 24 hours after he experienced the stroke; after five weeks of speech therapy his ability to talk continues to progressively improve and the residual deficits in his speech continue to resolve. Anticoagulation is required for stroke prevention in individuals with atrial fibrillation and atrial flutter. Warfarin, a vitamin K antagonist, is usually used for individuals with valvular atrial fibrillation. Direct oral anticoagulants have fewer bleeding complications and are usually recommended for nonvalvular atrial fibrillation; they include the direct thrombin inhibitor dabigatran or a factor ten a (Xa) inhibitor such as either apixaban, edoxaban, or rivaroxaban. Dysarthria is a common manifestation in stroke patients. Albeit, it is less common, isolated dysarthria without any other neurologic sequellae may be associated with stroke. Interventions encouraged by speech pathologists to enhance the resolution of post-stroke dysarthria include speaking louder to amplify the voice and exaggerating the movements of the mouth when speaking.

摘要

中风是常见的死亡原因。心血管疾病,包括心房颤动和心房扑动,是缺血性中风的常见病因。一名64岁男性以孤立性构音障碍为表现,无任何其他神经系统症状,诊断为因大脑中动脉闭塞导致的缺血性中风,影响了该动脉供血的皮质。他被发现处于心房扑动状态,这被确定为其中风的可能病因。他住院并接受肝素抗凝治疗;门诊时,使用直接口服抗凝药阿哌沙班维持抗凝治疗。需要用胺碘酮将他药物转复为正常窦性心律;他患有典型心房扑动,将接受心房扑动消融评估。他的构音障碍在中风后24小时内开始改善;经过五周的言语治疗,他的说话能力持续逐步提高,言语残留缺陷持续得到改善。心房颤动和心房扑动患者预防中风需要抗凝治疗。华法林是一种维生素K拮抗剂,通常用于瓣膜性心房颤动患者。直接口服抗凝药出血并发症较少,通常推荐用于非瓣膜性心房颤动;包括直接凝血酶抑制剂达比加群或Xa因子抑制剂,如阿哌沙班、依度沙班或利伐沙班。构音障碍是中风患者的常见表现。尽管较少见,但无任何其他神经系统后遗症的孤立性构音障碍可能与中风有关。言语病理学家鼓励的改善中风后构音障碍的干预措施包括大声说话以放大声音,说话时夸大嘴巴动作。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a7c5/10558244/cc2917f7f0ae/cureus-0015-00000044788-i01.jpg

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