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一名静脉血栓栓塞患者中因子V莱顿突变与凝血酶原基因G20210A突变的联合杂合性

The Combined Heterozygosity of Factor V Leiden and G20210A Prothrombin Gene Mutation in a Patient With Venous Thromboembolism.

作者信息

Machado Marcia, Cunha Marta, Gonçalves Filipe, Fernandes Carlos, Cotter Jorge

机构信息

Internal Medicine, Hospital da Senhora da Oliveira, Guimarães, PRT.

出版信息

Cureus. 2023 Sep 7;15(9):e44835. doi: 10.7759/cureus.44835. eCollection 2023 Sep.

DOI:10.7759/cureus.44835
PMID:37809238
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10559759/
Abstract

Venous thromboembolism (VTE) is a chronic illness that includes pulmonary embolism (PE) and deep vein thrombosis (DVT), and many risk factors are associated. Anticoagulation therapy remains the cornerstone of venous thromboembolism management, and the duration of anticoagulation depends on the risk of venous thromboembolism. We report a case of a female with a combined heterozygosity of factor V Leiden and G20210A prothrombin gene mutation.

摘要

静脉血栓栓塞症（VTE）是一种慢性疾病，包括肺栓塞（PE）和深静脉血栓形成（DVT），且存在多种相关危险因素。抗凝治疗仍然是静脉血栓栓塞症管理的基石，抗凝持续时间取决于静脉血栓栓塞症的风险。我们报告一例患有因子V莱顿和凝血酶原基因G20210A突变复合杂合性的女性病例。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5d2b/10559759/a853bc91cc25/cureus-0015-00000044835-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5d2b/10559759/7c591e299b56/cureus-0015-00000044835-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5d2b/10559759/a853bc91cc25/cureus-0015-00000044835-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5d2b/10559759/7c591e299b56/cureus-0015-00000044835-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5d2b/10559759/a853bc91cc25/cureus-0015-00000044835-i02.jpg

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