一项评估行为减肥计划在多发性硬化症患者中的预可行性的试点研究。
A pilot study evaluating the prefeasibility of a behavioral weight loss program in people with multiple sclerosis.
作者信息
Cozart Julia S, Bruce Amanda S, Befort Christie, Siengsukon Catherine, Lynch Sharon G, Punt Stephanie, Simon Stephen, Shook Robin P, Huebner Joanie, Bradish Taylor, Robichaud Jade, Bruce Jared M
机构信息
University of Missouri-Kansas City School of Medicine, Department of Biomedical and Health Informatics, 2411 Holmes St., Kansas City, MO, USA.
University of Missouri-Kansas City, Department of Psychology, 5030 Cherry St., Kansas City, MO, USA.
出版信息
Prev Med Rep. 2023 Sep 22;36:102437. doi: 10.1016/j.pmedr.2023.102437. eCollection 2023 Dec.
Weight loss interventions seldom include individuals with neurologic disease. The aims of the present study were to: 1) develop and assess the prefeasibility of a 6-month telehealth behavioral weight loss program for people with multiple sclerosis (MS) and obesity and 2) examine changes in weight loss (primary outcome), physical activity, and fruit/vegetable consumption at follow-up. Participants with obesity and MS engaged in a 24-week weight loss program. Participants followed established diet, exercise, and self-monitoring guidelines and attended weekly online group meetings. Median percentage weight loss was 10.54 % ( = 7.19). Participants who adhered more closely to the self-monitoring guidelines ( = 0.81, =.02), and who averaged higher weekly active minutes ( = 0.91, =.002) achieved greater percentage weight loss. Six of the eight pilot participants achieved clinically meaningful weight loss (>5%) after 6-months.
减肥干预措施很少将患有神经疾病的人纳入其中。本研究的目的是：1）为患有多发性硬化症（MS）和肥胖症的人群制定并评估一项为期6个月的远程医疗行为减肥计划的初步可行性，以及2）在随访时检查体重减轻（主要结果）、身体活动和水果/蔬菜摄入量的变化。患有肥胖症和MS的参与者参加了一项为期24周的减肥计划。参与者遵循既定的饮食、运动和自我监测指南，并参加每周的在线小组会议。体重减轻的中位数百分比为10.54%（标准差=7.19）。更严格遵循自我监测指南的参与者（相关系数=0.81，P值=0.02）以及每周平均活动分钟数更多的参与者（相关系数=0.91，P值=0.002）体重减轻的百分比更高。8名试点参与者中有6人在6个月后实现了具有临床意义的体重减轻（>5%）。
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