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[缺氧对猫小肠血管功能的直接影响]

[Direct effect of hypoxia on the functions of the small intestinal vessels of the cat].

作者信息

Polenov S A, Cherniavskaia G V

出版信息

Fiziol Zh SSSR Im I M Sechenova. 1986 Sep;72(9):1251-9.

PMID:3781055
Abstract

In anesthetized cats, artificial ventilation with 18, 14 and 8% O2 mixtures decreased the arterial blood pO2 from 104 to 85, 69 and 38 mm Hg, resp. Resistance of the intestine vessels and their capacity decreased in 14 and 8% O2; the capillary filtration coefficient increased at all levels of hypoxia whereas distensibility of veins and mean capillary hydrostatic pressure practically did not alter. A significant diminishing of constrictor responses of the intestine arterial vessels to noradrenaline only occurred in 8% O2. Precapillary sphincters are much more sensitive to O2 deficiency than other portions of the intensive vascular bed but their responsiveness to noradrenaline does not alter even in grave hypoxia.

摘要

在麻醉猫中,用含18%、14%和8%氧气的混合气体进行人工通气时,动脉血氧分压分别从104毫米汞柱降至85、69和38毫米汞柱。在含14%和8%氧气的情况下,肠血管阻力及其容量降低;在所有缺氧水平下,毛细血管滤过系数均增加,而静脉扩张性和平均毛细血管静水压实际上未改变。仅在含8%氧气的情况下,肠动脉血管对去甲肾上腺素的收缩反应才显著减弱。毛细血管前括约肌比密集血管床的其他部分对缺氧更敏感,但即使在严重缺氧时,它们对去甲肾上腺素的反应性也不会改变。

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