用于跨性别女性自杀筛查的患者健康问卷-9的验证
Validation of the Patient Health Questionnaire-9 for Suicide Screening in Transgender Women.
作者信息
Xu Lulu, Chang Ruijie, Wang Huwen, Xu Chen, Yu Xiaoyue, Chen Hui, Wang Rongxi, Liu Shangbin, Liu Yujie, Wang Ying, Cai Yong
机构信息
Department of Student Affairs, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
School of Public Health, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
出版信息
Transgend Health. 2023 Oct 4;8(5):450-456. doi: 10.1089/trgh.2021.0075. eCollection 2023 Oct.
PURPOSE
High prevalence of depression in transgender women highlights the importance of validating the measure to assess depression. Moreover, depression is significantly associated with suicide across research studies. The aims of the current study were to validate a Chinese-language version of the Patient Health Questionnaire-9 (PHQ-9) and to assess operating characteristics of the PHQ-9 for suicide screening in transgender women.
METHODS
With the approval of an Institutional Review Board (IRB), a total of 198 transgender women living in Shenyang, China, were recruited, and asked to complete the PHQ-9, including measures of their suicidal ideation, planning and attempt.
RESULTS
A one-factor model of the PHQ-9 was supported in the current sample, showing good reliability and validity. The best cutoff point for the PHQ-9 in suicidal ideation was 17, with a sensitivity/specificity of 77.78%; the best cutoff point for PHQ-9 in suicidal planning was 17, with a sensitivity of 81.82% and a specificity of 73.26%; and the best cutoff point for PHQ-9 in suicidal attempt was 20, with a sensitivity of 75% and a specificity of 90.21%.
CONCLUSION
Findings supported the validity of the PHQ-9. With potential clinical or research application, the PHQ-9 can be an efficient instrument for suicide screening in transgender women.
目的
跨性别女性中抑郁症的高患病率凸显了验证评估抑郁症测量方法的重要性。此外，在各项研究中，抑郁症与自杀显著相关。本研究的目的是验证中文版患者健康问卷-9（PHQ-9），并评估PHQ-9在跨性别女性自杀筛查中的操作特征。
方法
在机构审查委员会（IRB）批准后，招募了198名居住在中国沈阳的跨性别女性，并要求她们完成PHQ-9，包括对她们自杀意念、计划和未遂情况的测量。
结果
本样本支持PHQ-9的单因素模型，显示出良好的信度和效度。PHQ-9在自杀意念方面的最佳截断点为17，敏感度/特异度为77.78%；PHQ-9在自杀计划方面的最佳截断点为17，敏感度为81.82%，特异度为73.26%；PHQ-9在自杀未遂方面的最佳截断点为20，敏感度为75%，特异度为90.21%。
结论
研究结果支持PHQ-9的效度。鉴于其潜在的临床或研究应用价值，PHQ-9可成为跨性别女性自杀筛查的有效工具。
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