Department of Social Medicine and Health Management, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China.
Expert Rev Anti Infect Ther. 2023 Jul-Dec;21(12):1383-1388. doi: 10.1080/14787210.2023.2268280. Epub 2023 Nov 24.
This study aims to assess the prevalence and associated factors of non-adherence to antibiotics (NAA) during COVID-19.
A cross-sectional study was conducted from 28 October 2022 to 6 November 2022. A structured questionnaire was widely distributed on an online survey platform. Of the 8664 respondents, 7730 were included in the final analysis. Logistic regression analysis was used to examine the associated factors of NAA.
Of the 7730 participants, 17.83% reported antibiotic use in the past month, of which 53.05% had NAA. Those who aged over 60 years old, perceived their economy as good, had moderate or good antibiotic knowledge, and with high convenience to medical services and medicines were less likely to NAA ( < 0.05); while those with chronic diseases, living in Western or Northeastern China, and those who used non-prescription antibiotics were more likely to NAA ( < 0.05).
The prevalence of NAA remains at high levels in the general public. Targeted health education needs to be conducted in communities, pharmacies and health facilities to overcome misconceptions about antibiotics and to encourage people to seek formal medical care when ill, in order to improve public adherence to antibiotics.
本研究旨在评估 COVID-19 期间抗生素不依从（NAA）的流行情况及其相关因素。
本研究于 2022 年 10 月 28 日至 11 月 6 日开展了一项横断面研究。通过在线调查平台广泛分发了一份结构化问卷。在 8664 名受访者中，有 7730 名被纳入最终分析。采用 logistic 回归分析来检验 NAA 的相关因素。
在 7730 名参与者中，17.83%报告在过去一个月内使用过抗生素，其中 53.05%存在 NAA。年龄大于 60 岁、经济状况自评良好、具有中等或良好的抗生素知识、就医和购药便利性较高的参与者不太可能出现 NAA（ < 0.05）；而患有慢性病、居住在西部地区或东北地区、使用非处方抗生素的参与者更有可能出现 NAA（ < 0.05）。
普通人群中 NAA 的流行率仍然处于较高水平。需要在社区、药店和医疗机构开展有针对性的健康教育，以克服对抗生素的误解，并鼓励人们在患病时寻求正规医疗服务，从而提高公众对抗生素的依从性。
