Faculty of Health, Social Care & Medicine, Edge Hill University, Ormskirk, UK.
Faculty of Health, Social Care & Medicine, Edge Hill University, Ormskirk, UK; Cardio-Respiratory Research Centre, Edge Hill University, Ormskirk, Lancashire, UK.
Physiotherapy. 2023 Dec;121:37-45. doi: 10.1016/j.physio.2023.07.001. Epub 2023 Jul 8.
Evidence of the effectiveness of physiotherapy for bronchiectasis is inconsistent, partly due to variation in the selection and reporting of outcomes in clinical trials. This qualitative study is a component of the development of a core outcome set (COS). The COS will identify a minimum group of outcomes for use in clinical trials of physiotherapy considering the views of researchers, patients, and clinicians.
To identify outcomes for use in physiotherapy research that are important to patients and physiotherapists and to explain their significance.
Semi-structured interviews were conducted with adult patients with bronchiectasis who received physiotherapy, in addition to physiotherapists clinically involved in bronchiectasis care. Interviews were audio recorded and transcribed verbatim. Thematic analysis was used to identify, classify, and explain the significance of outcomes. Outcomes were mapped into the list created from literature review and classified into domains.
We interviewed 18 participants from four countries covering a range of experiences in different settings. Seventy outcomes were identified and grouped into 15 domains. Thirty-three outcomes were not previously reported in the literature. Thematic analysis revealed exacerbations, quality of life, use of healthcare resources, patient-reported symptoms, physical functioning, and sputum as the prominent themes reported by both patients and physiotherapists.
This qualitative study highlighted the importance of considering stakeholder perspectives when planning research trials. Outcomes identified will be used to inform the next phase of COS development.
This study is part of the COS development project registered with the Core Outcome Measures in Effectiveness Trials initiative (COMET) https://www.comet-initiative.org/Studies/Details/1931 CONTRIBUTION OF THE PAPER.
由于临床试验中结局的选择和报告存在差异，物理疗法治疗支气管扩张症的有效性证据并不一致。本定性研究是制定核心结局集（COS）的一部分。COS 将确定一组用于物理疗法临床试验的最小结局，同时考虑研究人员、患者和临床医生的观点。
确定对患者和物理治疗师重要的用于物理治疗研究的结局，并解释其重要性。
对接受过物理治疗的成年支气管扩张症患者以及临床参与支气管扩张症护理的物理治疗师进行半结构化访谈。访谈进行录音并逐字转录。采用主题分析来识别、分类和解释结局的意义。将结局映射到文献综述创建的列表中，并将其分类为各个领域。
我们采访了来自四个国家的 18 名参与者，他们在不同环境中具有不同的经验。共确定了 70 个结局，并将其分为 15 个领域。其中 33 个结局以前在文献中没有报道过。主题分析显示，恶化、生活质量、医疗资源的使用、患者报告的症状、身体功能和痰液是患者和物理治疗师都报告的突出主题。
本定性研究强调了在规划研究试验时考虑利益相关者观点的重要性。确定的结局将用于为 COS 开发的下一阶段提供信息。
本研究是在 COMET 倡议（https://www.comet-initiative.org/Studies/Details/1931）下的 COS 发展项目的一部分。
本文的贡献。
