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胃切除术后晚期倾倒综合征引起低血糖,二氮嗪治疗有效导致的终末期肾病。

End-stage Renal Disease in Which Diazoxide Was Effective in Treating Hypoglycemia Caused by Late Dumping Syndrome after Gastrectomy.

机构信息

Department of Internal Medicine, Meinan Hospital, Japan.

出版信息

Intern Med. 2024 May 15;63(10):1421-1427. doi: 10.2169/internalmedicine.1704-23. Epub 2023 Oct 6.

Abstract

We herein report a case in which diazoxide was effective in treating reactive hypoglycemia caused by late dumping syndrome in a patient with end-stage renal disease (ESRD). A 50-year-old man with ESRD and a history of gastrectomy underwent hemodialysis. Although he was administered voglibose to treat recurrent reactive hypoglycemia caused by late dumping syndrome, he had difficulty continuing treatment because of gastrointestinal side effects. When he began diazoxide treatment, the reactive hypoglycemia improved. The dose was gradually increased with no apparent side effects, and the hypoglycemic attacks disappeared one year after the start of treatment.

摘要

我们在此报告一例病例,其中硝苯地平在治疗终末期肾病(ESRD)患者晚期倾倒综合征引起的反应性低血糖方面有效。一名 50 岁男性患有 ESRD 和胃切除术病史,接受血液透析。尽管他服用了伏格列波糖来治疗晚期倾倒综合征引起的复发性反应性低血糖,但由于胃肠道副作用,他难以继续治疗。当他开始使用硝苯地平治疗时,反应性低血糖得到改善。剂量逐渐增加,没有明显的副作用,并且在开始治疗一年后低血糖发作消失。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6f87/11157299/81d793c8e061/1349-7235-63-1421-g001.jpg

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