Kanazawa Ken, Ito Takeki, HIjikata Mai, Kuwabara Koichiro
Department of Diabetes, Metabolism and Endocrinology, Japan Labor Health and Safety Organization, Tokyo Rosai Hospital, Tokyo, JPN.
Cureus. 2024 Dec 6;16(12):e75195. doi: 10.7759/cureus.75195. eCollection 2024 Dec.
Severe hypoglycemia (SH) is a significant risk, particularly in the elderly, and adrenal insufficiency (AI) may be a contributing factor. This study examines six cases of late dumping syndrome (LDS)-induced reactive hypoglycemia (RH), with AI as a potential trigger. Three of the six patients were diagnosed with AI, and one experienced a hypoglycemic coma. A significant correlation between blood glucose and insulin levels was found in the AI group. These findings suggest the potential role of AI in the development of SH in LDS patients after gastrectomy. Further research is needed for confirmation.
严重低血糖(SH)是一个重大风险,尤其是在老年人中,而肾上腺功能不全(AI)可能是一个促成因素。本研究调查了6例晚期倾倒综合征(LDS)诱发的反应性低血糖(RH)病例,其中AI可能是触发因素。6例患者中有3例被诊断为AI,1例发生低血糖昏迷。在AI组中发现血糖与胰岛素水平之间存在显著相关性。这些发现提示AI在胃切除术后LDS患者发生SH过程中可能发挥作用。需要进一步研究加以证实。