局部应用溴莫尼定致小眼球患者急性葡萄膜渗漏：一例报告

Topical brimonidine induced acute uveal effusion in a patient with nanophthalmos: a case report.

作者信息

Li Yakun, Zhou Qi

机构信息

Department of Ophthalmology, Peking Union Medical College, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Shuai Fu Yuan, Dongcheng District, Beijing, 100730, China.

Department of Ophthalmology, The Second Affiliated Hospital of Hebei North University, Zhangjiakou, 075100, China.

出版信息

BMC Ophthalmol. 2023 Oct 9;23(1):405. doi: 10.1186/s12886-023-03107-9.

DOI:10.1186/s12886-023-03107-9

PMID:37814274

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10561468/

Abstract

BACKGROUND

We report a case of uveal effusion in a nanophthalmic eye after topical use of brimonidine.

CASE PRESENTATION

A 42-year-old male patient with nanophthalmos experienced sudden blurred vision in the right eye after using topical brimonidine when picking up tennis balls repeatedly 6 weeks after bilateral YAG peripheral iridotomy. Ocular examination showed wide choroidal and exudative retinal detachment in the temporal and inferior region, involving the macula. Acute uveal effusion in the right, bilateral nanophthalmos was diagnosed. Oral and topical corticosteroids, combined with topical nonsteroids and atropine led to a complete resolution of the uveal effusion after one month.

CONCLUSION

This case suggested a possible causal relationship between the topical use of brimonidine and acute uveal effusion in patients with nanophthalmos. Topical brimonidine should be used with caution in nanophthalmic eyes.

摘要

背景

我们报告一例在小眼球局部使用溴莫尼定后发生葡萄膜渗漏的病例。

病例介绍

一名42岁小眼球男性患者，在双眼YAG周边虹膜切开术后6周反复捡网球时局部使用溴莫尼定后，右眼突然视力模糊。眼部检查显示颞侧和下方区域脉络膜广泛脱离及渗出性视网膜脱离，累及黄斑。诊断为双侧小眼球右眼急性葡萄膜渗漏。口服和局部使用皮质类固醇，联合局部使用非甾体类药物和阿托品，1个月后葡萄膜渗漏完全消退。