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创伤后应激障碍:药物及心理治疗干预的叙述性综述

Post-traumatic Stress Disorder: A Narrative Review of Pharmacological and Psychotherapeutic Interventions.

作者信息

Mansour Mohammad, Joseph Geethi Rose, Joy Golda K, Khanal Shandesh, Dasireddy Rachana Reddy, Menon Aardra, Barrie Mason Iyesatu, Kataria Janvi, Patel Tirath, Modi Shivani

机构信息

General Medicine, University of Debrecen, Debrecen, HUN.

General Medicine, Jordan University Hospital, Amman, JOR.

出版信息

Cureus. 2023 Sep 8;15(9):e44905. doi: 10.7759/cureus.44905. eCollection 2023 Sep.

Abstract

Post-traumatic stress disorder (PTSD) is a complex mental health condition affecting individuals exposed to traumatic events. This paper is a narrative review of the existing literature on pharmacological and psychotherapeutic interventions for PTSD. Treatment includes selective serotonin reuptake inhibitors (SSRIs), serotonin-norepinephrine reuptake inhibitors (SNRIs), and alpha-1 adrenergic receptor antagonists. By exploring the outcomes of these interventions, the review seeks to provide valuable insights into their potential as PTSD treatment options. The paper also highlights the importance of tailoring treatment plans to individual needs and discusses emerging treatments, such as mindfulness-based therapies, virtual reality therapy, and neurostimulation techniques. By integrating findings from various studies, it aims to offer valuable information to optimize treatment strategies and enhance outcomes for individuals suffering from PTSD. The goal is to support informed decision-making, ultimately leading to more effective and tailored approaches to address the challenges posed by this debilitating condition.

摘要

创伤后应激障碍(PTSD)是一种影响经历过创伤事件个体的复杂心理健康状况。本文是对现有关于PTSD药物和心理治疗干预文献的叙述性综述。治疗方法包括选择性5-羟色胺再摄取抑制剂(SSRIs)、5-羟色胺-去甲肾上腺素再摄取抑制剂(SNRIs)和α-1肾上腺素能受体拮抗剂。通过探讨这些干预措施的效果,本综述旨在为它们作为PTSD治疗选择的潜力提供有价值的见解。本文还强调了根据个体需求制定治疗计划的重要性,并讨论了新兴治疗方法,如正念疗法、虚拟现实疗法和神经刺激技术。通过整合各项研究的结果,其旨在提供有价值的信息,以优化治疗策略并改善PTSD患者的治疗效果。目标是支持明智的决策制定,最终带来更有效且更具针对性的方法来应对这种使人衰弱的疾病所带来的挑战。

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