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硫酸镁对支气管内超声检查期间综合肺指数评分及丙泊酚用量的影响:一项回顾性研究

The Effects of Magnesium Sulphate on Integrated Pulmonary Index Scores and Propofol Consumption During Endobronchial Ultrasonography: A Retrospective Study.

作者信息

Adıgüzel Şenay C, Akyurt Dilan, Gullu Arslan Nevra, Süren Mustafa

机构信息

Anesthesiology and Reanimation, Samsun University, Samsun, TUR.

Anesthesiology and Reanimation, Samsun University School of Medicine, Samsun Training and Research Hospital, Samsun, TUR.

出版信息

Cureus. 2023 Sep 8;15(9):e44880. doi: 10.7759/cureus.44880. eCollection 2023 Sep.

Abstract

Aim Our aim in this study was to investigate the effect of inhaled and intravenous (iv) magnesium (Mg) use on Integrated Pulmonary Index (IPI) score and propofol consumption in patients undergoing endobronchial ultrasonography (EBUS) procedure under sedoanalgesia. Materials and methods After obtaining the approval of the local ethics committee, the files of 96 patients aged 18-75 who underwent EBUS were reviewed retrospectively. Patients using Mg were classified as the M group, and patients not using Mg were classified as the control (C) group. IPI values, amount of propofol consumed, and intubation scores of group M and group C were evaluated. Results When the intubation score values ​​at the time of the bronchoscope passing through the vocal cords (assessment of vocal cord movement, cough reflex, and leg movement) during the EBUS procedure were compared, the intubation conditions were found to be significantly better in the M group than in the C group (p<0.05). Group M had less cough reflex than group C (p<0.05). IPI scores were significantly higher in the M group than in the C group at the 10th and 15th minutes (p<0.05). Total propofol consumption was found to be significantly lower in the M group (254.61±82.80 mg) than in the C group (321.25±90.04 mg) (p<0.05). Conclusion According to our results, the use of intravenous and inhaler Mg in addition to propofol sedation during the EBUS procedure may improve the respiratory parameters and can also significantly reduce the propofol dose.

摘要

目的 本研究旨在探讨在镇静镇痛下接受支气管内超声检查(EBUS)的患者中,吸入和静脉注射镁(Mg)对综合肺指数(IPI)评分及丙泊酚用量的影响。

材料与方法 在获得当地伦理委员会批准后,对96例年龄在18 - 75岁接受EBUS检查的患者资料进行回顾性分析。使用镁的患者归为M组,未使用镁的患者归为对照组(C组)。评估M组和C组的IPI值、丙泊酚用量及插管评分。

结果 在比较EBUS检查过程中支气管镜通过声带时的插管评分值(评估声带运动、咳嗽反射和腿部运动)时,发现M组的插管条件明显优于C组(p<0.05)。M组的咳嗽反射比C组少(p<0.05)。在第10分钟和第15分钟时,M组的IPI评分显著高于C组(p<0.05)。发现M组的丙泊酚总用量(254.61±82.80mg)明显低于C组(321.25±90.04mg)(p<0.05)。

结论 根据我们的结果,在EBUS检查过程中,除丙泊酚镇静外,静脉注射和吸入镁可能改善呼吸参数,还能显著降低丙泊酚剂量。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7eda/10560381/f7fd38e95a6e/cureus-0015-00000044880-i01.jpg

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