Que Suyun, Ma Xuanlei, Yang Tao, He Jiangtao
Dali Bai Autonomous Prefecture People's Hospital, Dali, China.
Jpn J Nurs Sci. 2024 Jan;21(1):e12559. doi: 10.1111/jjns.12559. Epub 2023 Oct 10.
To evaluate the effectiveness of herbal agents in the prevention and therapy of radiodermatitis in breast cancer patients.
Randomized controlled trials were searched from databases such as PubMed, Web of Science, Embase, Cochrane Library, and Chinese National Knowledge Infrastructure (CNKI) to assess the effectiveness of herbal agents compared to a standard medication or placebo in prevention or treatment of radiodermatitis in breast cancer.
Data from 16 studies involving 1994 patients were included. This meta-analysis included 10 clinical trials of 562 breast cancer patients treated with calendula, silymarin, or aloe vera for the prevention of radiodermatitis. Silymarin showed positive effects in ameliorating the damage of radiodermatitis, whereas the efficacy of calendula and aloe vera in the treatment of radiodermatitis lacks sufficient evidence.
Herbal medicine may show therapeutic effects on radiodermatitis in breast cancer, but more comprehensive investigations and clinical trials are required in the future.
评估草药制剂在预防和治疗乳腺癌患者放射性皮炎中的有效性。
从PubMed、科学网、Embase、Cochrane图书馆和中国知网等数据库中检索随机对照试验，以评估与标准药物或安慰剂相比，草药制剂在预防或治疗乳腺癌放射性皮炎方面的有效性。
纳入了16项研究的数据，涉及1994例患者。该荟萃分析包括10项临床试验，共562例乳腺癌患者接受了金盏花、水飞蓟宾或芦荟治疗以预防放射性皮炎。水飞蓟宾在改善放射性皮炎损伤方面显示出积极作用，而金盏花和芦荟治疗放射性皮炎的疗效缺乏充分证据。
草药可能对乳腺癌放射性皮炎有治疗作用，但未来需要更全面的研究和临床试验。
