Chen Xiaocen, Li Xueyu, Wang Zhao, Zheng Ruishuang, Zhang Fang, Zhao Jing, Liu Huiying, Luo Hongyuan
Department of Radiotherapy, Tianjin Medical University Cancer Institute & Hospital, National Clinical Research Center for Cancer, Tianjin's Clinical Research Center for Cancer, Key Laboratory of Breast Cancer Prevention and Therapy, Tianjin Medical University, Ministry of Education, Key Laboratory of Cancer Prevention and Therapy, Tianjin, China.
Department of Hepatobiliary Cancer, Tianjin Medical University Cancer Institute & Hospital, National Clinical Research Center for Cancer, Tianjin's Clinical Research Center for Cancer, Key Laboratory of Breast Cancer Prevention and Therapy, Tianjin Medical University, Ministry of Education, Key Laboratory of Cancer Prevention and Therapy, Tianjin, China.
Asia Pac J Oncol Nurs. 2024 Jul 14;11(9):100556. doi: 10.1016/j.apjon.2024.100556. eCollection 2024 Sep.
Up to now there is a lack of research to summarize the relevant evidence for radiation dermatitis (RD) management in patients with breast cancer. Therefore, this study aimed to summarize the best evidence for the prevention and management of RD in patients with breast cancer.
According to the "6S" evidence pyramid model, all major databases were searched from January 2018 to February 2024: UpToDate, BMJ Best Practice, National Guideline Clearinghouse, Guidelines International Network, MedSci, Yi Maitong Guidelines, National Comprehensive Cancer Network, Oncology Nursing Society, Radiology Assistant database, Society and College of Radiographers, Australian JBI Evidence-Based Health Care Center database, Cochrane Library, PubMed, CINAHL, Embase, Web of Science, China National Knowledge Infrastructure, Wangfang Data, Chinese Science and Technology Journal Database, Chinese Biology Medicine, etc.
A total of 22 articles which met the inclusion criteria were included in the study, comprising six guidelines, nine systematic reviews, four evidence summaries, one clinical decision, one expert consensus, and one randomized controlled trial. We summarized 35 pieces of evidence across four aspects: influence factor, evaluation and monitoring, prevention and treatment, care and health education.
This study provides a comprehensive summary of the best evidence for the prevention and management of RD in patients with breast cancer. It is recommended that subsequent evidence transformation should be conducted based on specific clinical circumstances to standardize the process of clinical prevention and management of RD.
This study was registered at the Fudan University Center for Evidence-Based Nursing (Registration No. ES20244311).
截至目前，缺乏对乳腺癌患者放射性皮炎（RD）管理相关证据进行总结的研究。因此，本研究旨在总结乳腺癌患者RD预防与管理的最佳证据。
根据“6S”证据金字塔模型，检索2018年1月至2024年2月期间所有主要数据库：UpToDate、BMJ最佳实践、国家指南资料库、指南国际网络、医脉通指南、美国国立综合癌症网络、肿瘤护理学会、放射学助手数据库、放射技师协会与学院、澳大利亚JBI循证卫生保健中心数据库、考克兰图书馆、PubMed、CINAHL、Embase、科学引文索引、中国知网、万方数据、中国科技期刊数据库、中国生物医学数据库等。
本研究共纳入22篇符合纳入标准的文章，包括6篇指南、9篇系统评价、4篇证据总结、1篇临床决策、1篇专家共识和1篇随机对照试验。我们从影响因素、评估与监测、预防与治疗、护理与健康教育四个方面总结了35条证据。
本研究全面总结了乳腺癌患者RD预防与管理的最佳证据。建议后续应根据具体临床情况进行证据转化，以规范RD临床预防与管理流程。
本研究在复旦大学循证护理中心注册（注册号：ES20244311）。
