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溴隐亭治疗痉挛性斜颈。一项双盲交叉研究。

Bromocriptine treatment of spasmodic torticollis. A double-blind crossover study.

作者信息

Juntunen J, Kaste M, Iivanainen M, Ranta T, Seppälä M

出版信息

Arch Neurol. 1979 Jul;36(7):449-50. doi: 10.1001/archneur.1979.00500430079017.

DOI:10.1001/archneur.1979.00500430079017
PMID:378199
Abstract

A double-blind crossover study (12 weeks and 12 weeks) was performed to evaluate the effects of bromocriptine on the symptoms and serum prolactin levels of 14 women with spasmodic torticollis. While the serum prolactin level decreased in response to bromocriptine, no difference was found between the effects of placebo and bromocriptine on the symptoms of spasmodic torticollis. Our findings suggest that dopaminergic neurotransmission is not involved in the pathogenesis of this syndrome.

摘要

开展了一项双盲交叉研究(12周和12周),以评估溴隐亭对14名痉挛性斜颈女性的症状和血清催乳素水平的影响。虽然血清催乳素水平因溴隐亭而降低,但安慰剂和溴隐亭对痉挛性斜颈症状的影响未发现差异。我们的研究结果表明,多巴胺能神经传递不参与该综合征的发病机制。

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Bromocriptine treatment of spasmodic torticollis. A double-blind crossover study.溴隐亭治疗痉挛性斜颈。一项双盲交叉研究。
Arch Neurol. 1979 Jul;36(7):449-50. doi: 10.1001/archneur.1979.00500430079017.
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