哮喘小鼠模型中的性别差异具有时间和组织隔间依赖性。
Sex differences in a murine model of asthma are time and tissue compartment dependent.
机构信息
Division of Allergy and Immunology, Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, United States of America.
Division of Allergic Diseases, Department of Medicine, Mayo Clinic, Rochester, MN, United States of America.
出版信息
PLoS One. 2023 Oct 11;18(10):e0271281. doi: 10.1371/journal.pone.0271281. eCollection 2023.
Abstract
Sexual dimorphism in lung inflammation is both time and tissue compartment dependent. Spatiotemporal variability in sex differences in a murine model of asthma must be accounted for when planning experiments to model the sex bias in allergic inflammation.
摘要
肺部炎症中的性别二态性既依赖于时间，也依赖于组织隔室。在计划模拟变应性炎症中性别偏向的实验时，必须考虑哮喘小鼠模型中性别差异的时空可变性。
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