一种用于检测感染路氏锥虫的大鼠血清中抑殖素的方法。

A method for the assay of ablastin in the serum of rats infected with Trypanosoma lewisi.

作者信息

Ferrante A, Drew P A, Jenkin C R

出版信息

Aust J Exp Biol Med Sci. 1978 Dec;56(6):741-5. doi: 10.1038/icb.1978.81.

DOI:10.1038/icb.1978.81

Abstract

This paper describes a simple quantitative assay for albastin, a factor present in the serum from rats infected with Trypanosoma lewisi, which prevents the division of the parasite. The assay measures in vitro the inhibition of the incorporation of 3H-TdR into the DNA of T. lewisi in the presence of serum from infected animals. Utilising this method, one can measure the titre of albastin in a particular serum sample and the time and duration of its appearance in the circulation of infected rats.

摘要

本文描述了一种针对阿尔巴斯丁的简单定量测定方法。阿尔巴斯丁是感染路氏锥虫的大鼠血清中存在的一种因子，可阻止该寄生虫的分裂。该测定方法在体外测量在感染动物血清存在的情况下，3H-胸苷掺入路氏锥虫DNA的抑制情况。利用这种方法，可以测量特定血清样本中阿尔巴斯丁的效价，以及其在感染大鼠血液循环中出现的时间和持续时间。

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A method for the assay of ablastin in the serum of rats infected with Trypanosoma lewisi.一种用于检测感染路氏锥虫的大鼠血清中抑殖素的方法。

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