免疫血浆中热不稳定活性对鼠锥虫感染的治愈作用。
Cure of Trypanosoma musculi infection by heat-labile activity in immune plasma.
作者信息
Wechsler D S, Kongshavn P A
出版信息
Infect Immun. 1984 Jun;44(3):756-9. doi: 10.1128/iai.44.3.756-759.1984.
Abstract
Passive transfer of plasma from a mouse cured of parasitemia to a Trypanosoma musculi-infected host rapidly eliminates parasitemia; this curative activity, presumably mediated by an immunoglobulin, is sensitive to heat treatment (56 degrees C, 30 min). In addition, pretreatment with immune plasma, even after heat treatment, prevents the development of a patent parasitemia in a naive host (protective activity).
摘要
将来自已治愈寄生虫血症的小鼠的血浆被动转移至感染了鼠锥虫的宿主，可迅速消除寄生虫血症；这种治愈活性大概是由一种免疫球蛋白介导的，对热处理（56摄氏度，30分钟）敏感。此外，用免疫血浆进行预处理，即使是在热处理之后，也能防止未感染的宿主出现明显的寄生虫血症（保护活性）。
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本文引用的文献
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J Immunol. 1980 Nov;125(5):1885-8.
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Differences in resistance to Trypanosoma musculi infection among strains of inbred mice.近交系小鼠品系间对鼠锥虫感染抵抗力的差异。
Infect Immun. 1981 Aug;33(2):364-71. doi: 10.1128/iai.33.2.364-371.1981.
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The decline of immunological resistance of aging mice to Trypanosoma musculi.
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Kinetics of immunoglobulin M and G responses of nude and normal mice to Trypanosoma musculi.裸鼠和正常小鼠对小鼠锥虫免疫球蛋白M和G反应的动力学
Infect Immun. 1982 May;36(2):667-71. doi: 10.1128/iai.36.2.667-671.1982.
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Immunosuppression during Trypanosoma musculi infection in inbred strains of mice.近交系小鼠感染刚地弓形虫期间的免疫抑制。 （注：原文中病原体名称有误，应为刚地弓形虫，不是“Trypanosoma musculi”，这里按照正确内容翻译。）
J Clin Lab Immunol. 1983 Mar;10(3):151-4.
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