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慢性下腰痛患者阿片类物质使用障碍诊断与物理治疗和整脊治疗使用之间的关联:基于群体的轨迹分析

Association of Opioid Use Disorder Diagnosis With Use of Physical Therapy and Chiropractic Care Among Chronic Low Back Pain Patients: A Group-Based Trajectory Analysis.

作者信息

Moyo Patience, Merlin Jessica S, George Miriam, Shireman Theresa I, Marshall Brandon D L

机构信息

Department of Health Services, Policy, and Practice, Brown University School of Public Health, Providence, Rhode Island.

Challenges in Managing and Preventing Pain Clinical Research Center, Division of General Internal Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania.

出版信息

J Pain. 2024 Mar;25(3):742-754. doi: 10.1016/j.jpain.2023.10.003. Epub 2023 Nov 22.

Abstract

Nonpharmacologic approaches are recommended as first-line treatment for chronic pain, and their importance is heightened among individuals with co-occurring opioid use disorder (OUD), in whom opioid therapies may be particularly detrimental. Our objectives were to assess the receipt and trajectories of nonpharmacologic pain treatment and determine the association of OUD diagnosis with these trajectories. This retrospective cohort study used Medicare claims data from 2016 to 2018 and applied group-based trajectory models to identify distinct patterns of physical therapy (PT) or chiropractic care treatment over the 12 months following a new episode of chronic low back pain. We used logistic regression models to estimate the association of co-occurring OUD with group membership in PT and chiropractic trajectories. Our sample comprised 607,729 beneficiaries at least 18 years of age, of whom 11.4% had a diagnosis of OUD. The 12-month prevalence of PT and chiropractic treatment receipt was 24.7% and 27.1%, respectively, and lower among Medicare beneficiaries with co-occurring OUD (PT: 14.6%; chiropractic: 6.8%). The final models identified 3 distinct trajectories each for PT (no/little use [76.6% of sample], delayed and increasing use [8.2%], and early and declining use [15.2%]); and chiropractic (no/little use [75.0% of sample], early and declining use [17.3%], and early and sustained use [7.7%]). People with OUD were more likely to belong in trajectories with little/no PT or chiropractic care as compared to other trajectories. The findings indicate that people with co-occurring chronic pain and OUD often do not receive early or any nonpharmacologic pain therapies as recommended by practice guidelines. PERSPECTIVE: PT and chiropractic care use were low overall and even lower among Medicare beneficiaries with co-occurring OUD compared with those without OUD. As updated guidelines on pain management are promulgated, targeted interventions (eg, insurance policy, provider, and patient education) are needed to ensure equitable access to guideline-recommended pain therapies.

摘要

非药物治疗方法被推荐作为慢性疼痛的一线治疗方法,对于同时患有阿片类药物使用障碍(OUD)的个体而言,其重要性更为突出,因为阿片类药物疗法对这类人群可能特别有害。我们的目标是评估非药物疼痛治疗的接受情况和轨迹,并确定OUD诊断与这些轨迹之间的关联。这项回顾性队列研究使用了2016年至2018年的医疗保险理赔数据,并应用基于组的轨迹模型来识别慢性下腰痛新发病例后12个月内物理治疗(PT)或整脊治疗的不同模式。我们使用逻辑回归模型来估计同时发生的OUD与PT和整脊轨迹中的组成员身份之间的关联。我们的样本包括607,729名至少18岁的受益人,其中11.4%被诊断患有OUD。PT和整脊治疗的12个月患病率分别为24.7%和27.1%,在同时患有OUD的医疗保险受益人中较低(PT:14.6%;整脊:6.8%)。最终模型确定了PT(无/很少使用[样本的76.6%]、延迟并增加使用[8.2%]、早期并减少使用[15.2%])和整脊(无/很少使用[样本的75.0%]、早期并减少使用[17.3%]、早期并持续使用[7.7%])各自的3种不同轨迹。与其他轨迹相比,患有OUD的人更有可能属于很少或没有接受PT或整脊治疗的轨迹。研究结果表明,同时患有慢性疼痛和OUD的人通常没有按照实践指南的建议接受早期或任何非药物疼痛治疗。观点:总体而言,PT和整脊治疗的使用率较低,与没有OUD的医疗保险受益人相比,同时患有OUD的受益人中使用率更低。随着疼痛管理更新指南的发布,需要有针对性的干预措施(例如保险政策、提供者和患者教育)来确保公平获得指南推荐的疼痛治疗。

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Factors mediating pain-related risk for opioid use disorder.介导阿片类药物使用障碍相关疼痛风险的因素。
Neuropharmacology. 2021 Mar 15;186:108476. doi: 10.1016/j.neuropharm.2021.108476. Epub 2021 Jan 30.

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