Cruz Vitor Alves, de Albuquerque Cleandro Pires, Guimarães Maria Fernanda Brandão de Resende, Dionello Carla da Fontoura, Ribeiro Sandra Lúcia Euzébio, de Souza Viviane Angelina, Gomes Ciro Martins, da Mota Licia Maria Henrique
Federal University of Goiás, Goiás, Brazil.
Department of Rheumatology, University of Brasilia, Brasilia, Brazil.
Front Med (Lausanne). 2023 Sep 25;10:1239775. doi: 10.3389/fmed.2023.1239775. eCollection 2023.
Leprosy is an infectious and contagious disease of slow evolution, triggered by . Arthritis is its third most common manifestation, after cutaneous and peripheral nerve involvement. Since musculoskeletal symptoms may be the initial presentation of the disease, it is important for health professionals to recognize its rheumatic manifestations for early diagnosis and appropriate treatment, especially in endemic areas. In addition, cases of leprosy have increased globally, notably in patients undergoing treatment with TNF-α blockers and due to the increase in migration and travel of people from developing countries to developed countries. This review proposes to discuss the main scenarios of mimicry of different rheumatic diseases by leprosy, as well as the role of immunosuppressive drugs used in rheumatology practice in the treatment of reactional states and in the risk of developing the infection.
麻风病是一种进展缓慢的传染性疾病，由……引发。关节炎是其第三常见的表现形式，仅次于皮肤和周围神经受累。由于肌肉骨骼症状可能是该疾病的首发表现，因此对于卫生专业人员来说，认识到其风湿性表现对于早期诊断和适当治疗非常重要，尤其是在流行地区。此外，全球麻风病病例有所增加，特别是在接受肿瘤坏死因子-α阻滞剂治疗的患者中，以及由于从发展中国家到发达国家的移民和旅行增加所致。本综述旨在讨论麻风病模仿不同风湿性疾病的主要情况，以及风湿病实践中使用的免疫抑制药物在治疗反应状态和感染风险方面的作用。
