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沙特阿拉伯肺炎和腹泻病例中抗生素滥用的患病率。

Prevalence of antibiotic misuse in cases of pneumonia and diarrhea in Saudi Arabia.

作者信息

Almughais Ebtehaj Saud, Alreshidi Fatmah Fahad, Ahmed Hussain Gadelkarim

机构信息

Department of Family and Community Medicine, College of Medicine, University of Hail, Hail - Saudi Arabia.

Department of Histopathology and Cytology, FMLS, University of Khartoum, Khartoum - Sudan.

出版信息

Drug Target Insights. 2023 Oct 9;17:114-119. doi: 10.33393/dti.2023.2614. eCollection 2023 Jan-Dec.

DOI:10.33393/dti.2023.2614
PMID:37822951
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10563503/
Abstract

BACKGROUND

Antibiotic misuse is a major public health issue with long-term repercussions.

OBJECTIVE

The purpose of this investigation was to evaluate the effects of pneumonia and diarrhea, with an emphasis on antibiotic misuse.

METHODOLOGY

This study included 410 participants (217 fathers and 193 mothers), of whom 239 purchased antibiotics for their children without a prescription, whereas 171 had a prescription or were unsure if one was required.

RESULTS

Antibiotics were used incorrectly by 58.1% of respondents. About 51.2% of participants said they were taking two antibiotics at the same time. Around 30% of people admitted to using antibiotics inefficiently. The most prevalent reason for use was "viral and bacterial," followed by "viral," and then "bacterial," with 35%, 21%, and 20%, respectively. In addition, 22.4% of patients have used antibiotics for an unknown reason.

CONCLUSION

Saudi parents of children with pneumonia and diarrhea abuse antibiotics. Saudi legislation banning medications without a prescription has helped reduce antibiotic abuse, but more community-based education and awareness are needed.

摘要

背景

抗生素滥用是一个具有长期影响的重大公共卫生问题。

目的

本调查的目的是评估肺炎和腹泻的影响,重点是抗生素滥用情况。

方法

本研究包括410名参与者(217名父亲和193名母亲),其中239人在没有处方的情况下为孩子购买抗生素,而171人有处方或不确定是否需要处方。

结果

58.1%的受访者抗生素使用不当。约51.2%的参与者表示他们同时服用两种抗生素。约30%的人承认抗生素使用效率低下。使用抗生素最普遍的原因是“病毒和细菌感染”,其次是“病毒感染”,然后是“细菌感染”,分别占35%、21%和20%。此外,22.4%的患者使用抗生素的原因不明。

结论

沙特患有肺炎和腹泻儿童的家长滥用抗生素。沙特禁止无处方用药的立法有助于减少抗生素滥用,但仍需要更多基于社区的教育和宣传。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ef6a/10563503/fd37b140a22f/dti-17-114_g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ef6a/10563503/2a1d7715ba9d/dti-17-114_g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ef6a/10563503/c0ff1c84bd77/dti-17-114_g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ef6a/10563503/7ace546f1172/dti-17-114_g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ef6a/10563503/fd37b140a22f/dti-17-114_g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ef6a/10563503/2a1d7715ba9d/dti-17-114_g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ef6a/10563503/c0ff1c84bd77/dti-17-114_g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ef6a/10563503/7ace546f1172/dti-17-114_g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ef6a/10563503/fd37b140a22f/dti-17-114_g004.jpg

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Antibiotics Self Medication among Children: A Systematic Review.儿童自我使用抗生素:一项系统评价
Antibiotics (Basel). 2022 Nov 9;11(11):1583. doi: 10.3390/antibiotics11111583.
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Evolutionary optimisation of antibiotic dosing regimens for bacteria with different levels of resistance.针对具有不同耐药水平的细菌,对抗生素给药方案进行进化优化。
Artif Intell Med. 2022 Nov;133:102405. doi: 10.1016/j.artmed.2022.102405. Epub 2022 Sep 24.
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Accelerated spread of antibiotic resistance genes (ARGs) induced by non-antibiotic conditions: Roles and mechanisms.非抗生素条件诱导的抗生素耐药基因(ARGs)的加速传播:作用和机制。
Water Res. 2022 Oct 1;224:119060. doi: 10.1016/j.watres.2022.119060. Epub 2022 Sep 6.
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Restriction on antimicrobial dispensing without prescription on a national level: Impact on the overall antimicrobial utilization in the community pharmacies in Saudi Arabia.国家层面限制无处方配药抗菌药物:对沙特阿拉伯社区药店整体抗菌药物使用的影响。
PLoS One. 2022 Jul 26;17(7):e0271188. doi: 10.1371/journal.pone.0271188. eCollection 2022.
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