大鼠饥饿过程中有机酸和挥发性代谢产物的尿液特征
Urinary profiles of organic acids and volatile metabolites during the starvation process in rats.
作者信息
Yancey M, Holland M L, Stuart R, Wiesler D, Novotny M
出版信息
J Chromatogr. 1986 Oct 31;382:3-18. doi: 10.1016/s0378-4347(00)83499-4.
PMID:3782399
Abstract
Capillary gas chromatographic procedures were used to quantify the volatile and acidic compound profiles in the urinary samples of Sprague-Dawley rats during the starvation and refeeding periods. Numerous metabolites, identified through mass spectrometry, showed significant variations due to these physiological processes. Correlations are attempted with the previously studied biochemical processes in diabetic animals.
摘要
采用毛细管气相色谱法对斯普拉格-道利大鼠在饥饿和再喂养期间尿液样本中的挥发性和酸性化合物谱进行定量分析。通过质谱鉴定出的大量代谢物显示，由于这些生理过程存在显著差异。尝试将其与先前在糖尿病动物中研究的生化过程进行关联。
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