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High-performance liquid chromatographic analysis of piroxicam and its major metabolite 5'-hydroxypiroxicam in human plasma and urine.

作者信息

Richardson C J, Ross S G, Blocka K L, Verbeeck R K

出版信息

J Chromatogr. 1986 Oct 31;382:382-8. doi: 10.1016/s0378-4347(00)83548-3.

DOI:10.1016/s0378-4347(00)83548-3
PMID:3782409
Abstract
摘要

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High-performance liquid chromatographic analysis of piroxicam and its major metabolite 5'-hydroxypiroxicam in human plasma and urine.人血浆和尿液中吡罗昔康及其主要代谢物5'-羟基吡罗昔康的高效液相色谱分析
J Chromatogr. 1986 Oct 31;382:382-8. doi: 10.1016/s0378-4347(00)83548-3.
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Quantification of piroxicam and 5'-hydroxypiroxicam in human plasma and saliva using liquid chromatography-tandem mass spectrometry following oral administration.口服给药后，采用液相色谱-串联质谱法对人血浆和唾液中的吡罗昔康和5'-羟基吡罗昔康进行定量分析。
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Piroxicam and 5'-hydroxypiroxicam kinetics following multiple dose administration of piroxicam.吡罗昔康多次给药后的吡罗昔康和5'-羟基吡罗昔康动力学
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Simultaneous determination of piroxicam and its major metabolite 5'-hydroxypiroxicam in human plasma by derivative spectrophotometry.导数分光光度法同时测定人血浆中吡罗昔康及其主要代谢物5'-羟基吡罗昔康
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Effective method for the detection of piroxicam in human plasma using HPLC.使用高效液相色谱法检测人血浆中吡罗昔康的有效方法。
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Br J Clin Pharmacol. 1994 Jan;37(1):1-5. doi: 10.1111/j.1365-2125.1994.tb04230.x.

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Effect of induced hypoalbuminemia on distribution, total clearance and unbound clearance of piroxicam in vivo in the rat.诱导性低白蛋白血症对大鼠体内吡罗昔康分布、总清除率及非结合清除率的影响。
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Pharmacokinetics of oxicam nonsteroidal anti-inflammatory agents.昔康类非甾体抗炎药的药代动力学
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Oral bioavailability of CHF1194, an inclusion complex of piroxicam and beta-cyclodextrin, in healthy subjects under single dose and steady-state conditions.
吡罗昔康与β-环糊精包合物CHF1194在健康受试者单剂量和稳态条件下的口服生物利用度。
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Piroxicam-beta-cyclodextrin. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic potential in rheumatic diseases and pain states.吡罗昔康-β-环糊精。对其药效学和药代动力学特性以及在风湿性疾病和疼痛状态中的治疗潜力的综述。
Drugs. 1994 Dec;48(6):907-29. doi: 10.2165/00003495-199448060-00007.
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Piroxicam and 5'-hydroxypiroxicam kinetics following multiple dose administration of piroxicam.吡罗昔康多次给药后的吡罗昔康和5'-羟基吡罗昔康动力学
Eur J Clin Pharmacol. 1987;32(1):89-91. doi: 10.1007/BF00609964.
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A lack of pharmacokinetic interaction between ranitidine and piroxicam.雷尼替丁与吡罗昔康之间不存在药代动力学相互作用。
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Steady state pharmacokinetics of piroxicam in children with rheumatic diseases.吡罗昔康在风湿性疾病患儿中的稳态药代动力学。
Eur J Clin Pharmacol. 1991;41(1):79-81. doi: 10.1007/BF00280114.