Miyazawa H
Nihon Seikeigeka Gakkai Zasshi. 1986 Aug;60(8):1003-16.
To clarify the significance of muscle tension and the effect of electrical stimulation on the immobilized muscle, two experiments were performed. First, the ankle joint of rat was fixed by a Kirschner-wire in two ways. After fixation at a strained position for one to twelve weeks, wet weight of soleus had decreased less than after fixation at a relaxed position. Histochemical investigation revealed the fiber type transformation of soleus from type 1 to type 2 at relaxed position, which was not observed at a strained position. The result confirmed the importance of muscle tension not only in the nutrition but also in the differentiation of the muscle. Secondly, electrical stimulation was given to the immobilized soleus for two weeks. Under the experimental procedure, the electrical stimulation prevented the transformation of muscle fiber type, but not muscle atrophy. This result suggested that the nutrition and the differentiation of muscle could be regulated independently.
为阐明肌肉张力的意义以及电刺激对固定肌肉的影响，进行了两项实验。首先，以两种方式用克氏针固定大鼠的踝关节。在应变位置固定一至十二周后，比目鱼肌的湿重减少量小于在松弛位置固定后的减少量。组织化学研究显示，在松弛位置比目鱼肌纤维类型从1型转变为2型，而在应变位置未观察到这种转变。该结果证实了肌肉张力不仅在肌肉营养方面而且在肌肉分化方面的重要性。其次，对固定的比目鱼肌进行两周的电刺激。在该实验过程中，电刺激阻止了肌纤维类型的转变，但未阻止肌肉萎缩。该结果表明，肌肉的营养和分化可以独立调节。
