Schultz Kris Ann P, Chintagumpala Murali, Piao Jin, Chen Kenneth S, Shah Rachana, Gartrell Robyn D, Christison-Lagay Emily, Pashnakar Farzana, Berry Jesse L, O'Neill Allison F, Vasta Lauren M, Flynn Ashley, Mitchell Sarah G, Seynnaeve Brittani Kn, Rosenblum Jeremy, Potter Samara L, Kamihara Junne, Rodriguez-Galindo Carlos, Hawkins Douglas S, Laetsch Theodore W
Cancer and Blood Disorders, Children's Minnesota, Minneapolis, MN.
Division of Hematology-Oncology, Department of Pediatrics, Texas Children's Cancer Center, Baylor College of Medicine, Houston, TX.
EJC Paediatr Oncol. 2023 Dec;2. doi: 10.1016/j.ejcped.2023.100024. Epub 2023 Jul 20.
While all childhood cancers are rare, tumors that are particularly infrequent or underrepresented within pediatrics are studied under the umbrella of the Children's Oncology Group Rare Tumor committee, divided into the Retinoblastoma and Infrequent Tumor subcommittees. The Infrequent Tumor subcommittee has traditionally included an emphasis on globally rare tumors such as adrenocortical carcinoma, nasopharyngeal carcinoma, or those tumors that are rare in young children, despite being common in adolescents and young adults, such as colorectal carcinoma, thyroid carcinoma, and melanoma. Pleuropulmonary blastoma, gonadal stromal tumors, pancreatic tumors including pancreatoblastoma, gastrointestinal stromal tumor, nonmelanoma skin cancers, neuroendocrine tumors, and desmoplastic small round cell tumors, as well as other carcinomas are also included under the heading of the Children's Oncology Group Rare Tumor committee. While substantial challenges exist in rare cancers, inclusion and global collaboration remain key priorities to ensure high quality research to advance care.
虽然所有儿童癌症都很罕见，但在儿科中特别罕见或研究较少的肿瘤在儿童肿瘤学组罕见肿瘤委员会的框架下进行研究，该委员会分为视网膜母细胞瘤和罕见肿瘤小组委员会。罕见肿瘤小组委员会传统上一直侧重于全球罕见的肿瘤，如肾上腺皮质癌、鼻咽癌，或那些在幼儿中罕见但在青少年和年轻成年人中常见的肿瘤，如结直肠癌、甲状腺癌和黑色素瘤。儿童肿瘤学组罕见肿瘤委员会的范畴还包括胸膜肺母细胞瘤、性腺间质肿瘤、胰腺肿瘤（包括成胰细胞瘤）、胃肠道间质瘤、非黑色素瘤皮肤癌、神经内分泌肿瘤、促纤维增生性小圆细胞瘤以及其他癌症。尽管罕见癌症存在重大挑战，但纳入研究和全球合作仍然是确保高质量研究以推进医疗护理的关键优先事项。
