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[杜氏肌营养不良症手指畸形的功能与解剖学研究]

[A functional and anatomical study of finger deformities in Duchenne muscular dystrophy].

作者信息

Morita H

出版信息

Nihon Seikeigeka Gakkai Zasshi. 1986 Aug;60(8):989-1002.

PMID:3782972
Abstract

Functional and anatomical studies were performed on 145 patients with Duchenne muscular dystrophy. In the early stage, finger deformities were characterized by hyperextension of the PIP joint together with an extended MP joint, while the DIP joint was extended or flexed. At the advanced stage, the MP joint tended to flex while the position of the PIP and DIP joint remained unchanged. In addition, various modified deformities were observed in a small number of fingers. At the terminal stage, the MP joint, including the PIP and DIP joints, exhibited contracture. The following pathomechanic factors in finger deformities were considered to be important in the development of muscle atrophy and degeneration: Muscle imbalance between weakened extrinsic muscles and not severely weakened intrinsic muscles, retraction of muscles and tendons, and deviation of finger tendons.

摘要

对145例杜氏肌营养不良患者进行了功能和解剖学研究。在早期,手指畸形的特征是近端指间关节过伸,同时掌指关节伸展,而远端指间关节伸展或屈曲。在晚期,掌指关节倾向于屈曲,而近端指间关节和远端指间关节的位置保持不变。此外,在少数手指中观察到各种改良畸形。在终末期,包括近端指间关节和远端指间关节在内的掌指关节出现挛缩。手指畸形的以下病理力学因素被认为在肌肉萎缩和变性的发展中很重要:外在肌无力与内在肌未严重减弱之间的肌肉失衡、肌肉和肌腱的回缩以及手指肌腱的偏移。

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