Alqahtani Elham, Albalawi Yara, Altwaijri Nouf A, Alqahtani Lama, Alshail Shahad
Ophthalmology, King Faisal Specialist Hospital and Research Centre, Riyadh, SAU.
Orthopedic Surgery, King Saud Medical City, Riyadh, SAU.
Cureus. 2023 Sep 10;15(9):e44994. doi: 10.7759/cureus.44994. eCollection 2023 Sep.
Nonspecific orbital inflammation (NSOI), the primary cause of painful orbitopathy mostly in adults, can either manifest as localized or diffused. Periorbital edema or swelling is the most common sign followed by proptosis. NSOI or orbital pseudomotor secondary to systemic lupus erythematosus (SLE) is very uncommon in the Kingdom of Saudi Arabia. This is the first reported case from Saudi Arabia. The patient first presented to the outpatient department during her gestational period. Her chief complaint was right eye swelling and pain when she woke up in the morning. Her past medical history was positive for irritable bowel disease and SLE. A slit lamp examination revealed chemosis with conjunctival injections in the right eye and mild temporal chemosis in the left eye. Funduscopic examination after pupillary dilation revealed hyperemic discs with venous tortuosity more prominent in the right eye. Serum albumin level was low at 29 g/L. Orbital magnetic resonance imaging without contrast showed bilateral diffuse preseptal soft tissue swelling more prominent on the right side with diffuse bilateral congestion of intraorbital fat, including intraconal and extraconal fat. There was associated fat stranding around the optic nerves bilaterally. The bilateral extraocular muscles showed a diffusely increased T2 signal compatible with edema. The patient was given a bolus of intravenous methylprednisolone for three days. She had a satisfactory recovery. Early diagnosis is important to rule out other differential diagnoses, such as orbital cellulitis and lymphoma.
非特异性眼眶炎症(NSOI)是成人眼眶疼痛性病变的主要原因,可表现为局限性或弥漫性。眶周水肿或肿胀是最常见的体征,其次是眼球突出。继发于系统性红斑狼疮(SLE)的NSOI或眼眶假瘤在沙特阿拉伯王国非常罕见。这是沙特阿拉伯首例报告病例。患者首次在孕期就诊于门诊。她的主要诉求是早晨醒来时右眼肿胀疼痛。她既往有肠易激综合征和SLE病史。裂隙灯检查显示右眼结膜充血伴球结膜水肿,左眼轻度颞侧球结膜水肿。散瞳后眼底检查显示视盘充血,静脉迂曲,右眼更明显。血清白蛋白水平低,为29 g/L。眼眶磁共振成像平扫显示双侧弥漫性眶隔前软组织肿胀,右侧更明显,眶内脂肪包括肌锥内和肌锥外脂肪弥漫性双侧充血。双侧视神经周围有脂肪条索。双侧眼外肌T2信号弥漫性增高,符合水肿表现。患者接受了为期三天的静脉注射甲泼尼龙冲击治疗。她恢复良好。早期诊断对于排除其他鉴别诊断如眼眶蜂窝织炎和淋巴瘤很重要。