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维拉帕米致命过量中毒的毒理学发现。

Toxicological findings in a fatal overdose of verapamil.

作者信息

Crouch D J, Crompton C, Rollins D E, Peat M A, Francom P

出版信息

J Forensic Sci. 1986 Oct;31(4):1505-8.

PMID:3783117
Abstract

Presented is a case where the death was attributed to the deliberate ingestion of an overdose of verapamil (V). Blood, urine, and gastric concentrations of the drug were determined by gas chromatography with nitrogen phosphorus detection (GC-NPD). Identification of norverapamil (NV) was made. A presumptive identification of o-demethylnorverapamil (DNV) was also made.

摘要

本文呈现了一例死亡被归因于故意过量服用维拉帕米(V)的病例。通过带氮磷检测的气相色谱法(GC-NPD)测定了该药物在血液、尿液和胃中的浓度。鉴定出了去甲维拉帕米(NV),还初步鉴定出了邻去甲基去甲维拉帕米(DNV)。

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