Le Quesne P M, Fowler C J
J Neurol Neurosurg Psychiatry. 1986 Oct;49(10):1191-4. doi: 10.1136/jnnp.49.10.1191.
Pain thresholds to a pinch stimulus were measured at eight sites on the dorsum of both feet from 17 diabetic patients. Sixteen feet had neuropathic ulcers and seven had Charcot arthropathy. Vibration perception thresholds, radial nerve action potentials, muscle action potentials of flexor digitorum brevis, autonomic cardiovascular reflexes and reflex sweat output were also measured. Pinch pain threshold was abnormal in 15 diabetic feet, 11 having one or more insensitive sites. There was a greater variability in threshold between sites tested in diabetic than control subjects.
对17名糖尿病患者双脚背部的8个部位进行了捏压刺激疼痛阈值测量。16只脚患有神经性溃疡,7只患有夏科氏关节病。还测量了振动觉阈值、桡神经动作电位、趾短屈肌肌肉动作电位、自主心血管反射和反射性出汗量。15只糖尿病足的捏压疼痛阈值异常,其中11只存在一个或多个感觉迟钝部位。与对照组相比,糖尿病患者测试部位之间的阈值变异性更大。