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一项关于患有神经性足部病变的糖尿病患者疼痛阈值的研究。

A study of pain threshold in diabetics with neuropathic foot lesions.

作者信息

Le Quesne P M, Fowler C J

出版信息

J Neurol Neurosurg Psychiatry. 1986 Oct;49(10):1191-4. doi: 10.1136/jnnp.49.10.1191.

DOI:10.1136/jnnp.49.10.1191
PMID:3783181
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1029055/
Abstract

Pain thresholds to a pinch stimulus were measured at eight sites on the dorsum of both feet from 17 diabetic patients. Sixteen feet had neuropathic ulcers and seven had Charcot arthropathy. Vibration perception thresholds, radial nerve action potentials, muscle action potentials of flexor digitorum brevis, autonomic cardiovascular reflexes and reflex sweat output were also measured. Pinch pain threshold was abnormal in 15 diabetic feet, 11 having one or more insensitive sites. There was a greater variability in threshold between sites tested in diabetic than control subjects.

摘要

对17名糖尿病患者双脚背部的8个部位进行了捏压刺激疼痛阈值测量。16只脚患有神经性溃疡,7只患有夏科氏关节病。还测量了振动觉阈值、桡神经动作电位、趾短屈肌肌肉动作电位、自主心血管反射和反射性出汗量。15只糖尿病足的捏压疼痛阈值异常,其中11只存在一个或多个感觉迟钝部位。与对照组相比,糖尿病患者测试部位之间的阈值变异性更大。

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A study of pain threshold in diabetics with neuropathic foot lesions.一项关于患有神经性足部病变的糖尿病患者疼痛阈值的研究。
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引用本文的文献

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Diabet Foot Ankle. 2016 Sep 29;7:31922. doi: 10.3402/dfa.v7.31922. eCollection 2016.
2
Nociception at the diabetic foot, an uncharted territory.糖尿病足的伤害感受:一个未知领域。
World J Diabetes. 2015 Apr 15;6(3):391-402. doi: 10.4239/wjd.v6.i3.391.
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The natural course of peripheral and autonomic neural function during the first two years after diagnosis of type 1 diabetes.1型糖尿病确诊后最初两年外周及自主神经功能的自然病程。
Klin Wochenschr. 1988 Nov 1;66(21):1085-92. doi: 10.1007/BF01711924.
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Selective neuropathy and preserved vascular responses in the diabetic Charcot foot.糖尿病夏科氏足中的选择性神经病变与保留的血管反应
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本文引用的文献

1
The diabetic leg.糖尿病足
Diabetologia. 1982 Mar;22(3):141-7. doi: 10.1007/BF00283741.
2
Progressive centripetal degeneration of axons in small fibre diabetic polyneuropathy.小纤维糖尿病性多发性神经病中轴突进行性向心性变性。
Brain. 1983 Dec;106 ( Pt 4):791-807. doi: 10.1093/brain/106.4.791.
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Sympathetic nerve failure in diabetes.糖尿病中的交感神经功能衰竭。
Diabetologia. 1983 Aug;25(2):73-7. doi: 10.1007/BF00250890.
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Quantitative sudomotor axon reflex test in normal and neuropathic subjects.正常人和神经病变患者的定量汗腺轴突反射试验
Ann Neurol. 1983 Nov;14(5):573-80. doi: 10.1002/ana.410140513.
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Evaluation of thermal and vibration sensation in diabetic neuropathy.糖尿病性神经病变中热觉与振动觉的评估
Diabetologia. 1985 Mar;28(3):131-7. doi: 10.1007/BF00273859.
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The aetiology of diabetic neuropathic ulceration of the foot.
Br J Surg. 1985 Jan;72(1):1-6. doi: 10.1002/bjs.1800720102.
7
A comparison of four tests for assessing the pain sensitivity of different subjects and test areas.四种用于评估不同受试者和测试区域疼痛敏感性的测试方法的比较。
Pain. 1977 Aug;3(4):353-365. doi: 10.1016/0304-3959(77)90065-3.