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儿童危重症患儿父母创伤后应激障碍的流行趋势及危险因素:荟萃分析和亚组分析证据。

Epidemical trends and risk factors of PTSD in parents of critically ill children: Evidence from both meta-analysis and subgroup analysis.

机构信息

Department of Epidemiology and Health Statistics, School of Public Health, Zunyi Medical University, Zunyi, Guizhou, China.

Department of Epidemiology and Health Statistics, School of Public Health, Zunyi Medical University, Zunyi, Guizhou, China.

出版信息

J Affect Disord. 2024 Jan 1;344:242-251. doi: 10.1016/j.jad.2023.10.032. Epub 2023 Oct 12.

DOI:10.1016/j.jad.2023.10.032
PMID:37832741
Abstract

BACKGROUND

Post-Traumatic Stress Disorder (PTSD) in parents traumatized by a child's critical illness, while differences in prevalence and risk factors for parental PTSD in previous studies. This study aimed to assess trends in the prevalence and risk factors for PTSD in parents of critically ill children.

METHODS

Nine main databases were searched to extract the prevalence, sample size and risk factors from the published literature. Random effects model analysis, I statistic, quality assessment, subgroup analysis and sensitivity analysis were performed.

RESULTS

Twenty-five studies met the inclusion criteria, with pooled prevalence rates of 13.8 % (95 % CI: [confidence interval, CI] 10.0 %-17.7 %) in fathers and 20.2 % (95 % CI:16.1 %-24.3 %) in mothers. Mothers had a significantly higher prevalence of PTSD compared to fathers. The prevalence of PTSD generally increased after discharge, with the highest prevalence at 6 months, but then decreased (fathers: 18.0 %, CI: 6.1 %-29.9 %; mothers: 20.2 %, CI: 12.8 %-27.6 %), respectively. The results showed five risks, positive acute stress disorder (ASD) screening (OR [odds ratio, OR] =2.45), disease severity (OR = 3.78), perceived stress (OR = 1.44), unemployed status (OR = 2.52) and length of hospital stay (OR = 1.01).

LIMITATIONS

Due to the limitations of the original study, we could not explore trends in the prevalence of PTSD in this particular population over a more extended period after hospital discharge.

CONCLUSION

The prevalence of PTSD among parents of critically ill children is high and significantly different. Therefore, it is crucial to focus on this vulnerable group, providing them with essential psychological counseling and comprehensive social support to reduce the occurrence of PTSD.

摘要

背景

创伤后应激障碍(PTSD)在父母中发生创伤性儿童疾病,而以往研究中父母 PTSD 的患病率和危险因素存在差异。本研究旨在评估危重病儿童父母 PTSD 的患病率和危险因素的趋势。

方法

从已发表的文献中提取患病率、样本量和危险因素,检索 9 个主要数据库。采用随机效应模型分析、I 统计量、质量评估、亚组分析和敏感性分析。

结果

符合纳入标准的 25 项研究,父亲 PTSD 的总患病率为 13.8%(95%可信区间:[置信区间,CI] 10.0%-17.7%),母亲为 20.2%(95%CI:16.1%-24.3%)。母亲 PTSD 的患病率明显高于父亲。出院后 PTSD 的患病率普遍升高,6 个月时患病率最高,但随后下降(父亲:18.0%,CI:6.1%-29.9%;母亲:20.2%,CI:12.8%-27.6%)。结果显示有 5 个危险因素,即阳性急性应激障碍(ASD)筛查(OR=2.45)、疾病严重程度(OR=3.78)、感知压力(OR=1.44)、失业状态(OR=2.52)和住院时间(OR=1.01)。

局限性

由于原始研究的限制,我们无法在出院后更长的时间内探讨这一特定人群 PTSD 患病率的变化趋势。

结论

危重病儿童父母 PTSD 的患病率较高且差异显著。因此,关注这一脆弱群体至关重要,为其提供必要的心理咨询和全面的社会支持,以减少 PTSD 的发生。

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