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中药莪术治疗脑胶质瘤的研究进展。

A review of traditional Chinese medicine Curcumae Rhizoma for treatment of glioma.

机构信息

The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangdong Province Hospital of Chinese Medicine, Guangzhou, Guangdong Province, P.R. China; The Second Clinical College of Guangzhou University of Chinese Medicine, Guangzhou, Guangdong Province, P.R. China.

The Second Clinical College of Guangzhou University of Chinese Medicine, Guangzhou, Guangdong Province, P.R. China.

出版信息

Int Rev Neurobiol. 2023;172:303-319. doi: 10.1016/bs.irn.2023.07.004. Epub 2023 Sep 19.

Abstract

Glioma is the most common primary central nervous tumor and its malignant and high recurrence rate are seriously threatening patient's life. The prognosis of glioma patients is still poor with a variety of modern treatments. Traditional Chinese medicine (TCM) is widely used in the adjuvant treatment or alternative medicine of glioma. Curcumae Rhizoma is one of the most commonly used in traditional Chinese medicine prescriptions for its anti-tumor characteristics. There are also many studies that reveals the anti-tumor effect of its active ingredients and some of which have been made into drugs and have been used in clinical practice. This review summarizes the new research progress on Curcumae Rhizoma for the treatment of glioma in recent years.

摘要

脑胶质瘤是最常见的原发性中枢神经系统肿瘤,其恶性程度高、复发率高,严重威胁患者生命。尽管采用了多种现代治疗方法,脑胶质瘤患者的预后仍然较差。在脑胶质瘤的辅助治疗或替代医学中,中药(TCM)被广泛应用。莪术因其具有抗肿瘤特性,是中药方剂中最常用的药物之一。也有许多研究揭示了其活性成分的抗肿瘤作用,其中一些已被制成药物并应用于临床实践。本综述总结了近年来莪术治疗脑胶质瘤的新研究进展。

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